HitPredict

Interactor 1: IRF1 (P10914)
Interferon regulatory factor 1 (IRF-1)
Gene: IRF1

Interactor 2: CHIP (Q9UNE7)
E3 ubiquitin-protein ligase CHIP (EC 2.3.2.27) (Antigen NY-CO-7) (CLL-associated antigen KW-8) (Carboxy terminus of Hsp70-interacting protein) (RING-type E3 ubiquitin transferase CHIP) (STIP1 homology and U box-containing protein 1)
Gene: STUB1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.93	0.60	0.749

Property	Details
Experiments	26330542, 28362432, 30042418, 20947504, 23134341, 35972291, 23729439
Identification Methods	enzymatic study, affinity chromatography technology, pull down
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 325 Hs			1 303
+	Hs
		183102 IRF8_HUMAN (7-270): 1.22e-99: 301: 28.79		KDM6A_HUMAN (25-206): 2.59e-10: 63.1: 13.02
+	Hs
		297058 IRF3_HUMAN (1-263): 7.43e-62: 204: 21.29		TOM70_HUMAN (4-212): 8.69e-40: 148: 22.47
+	Hs
		213546 IRF3_HUMAN (1-263): 7.43e-62: 204: 21.29		SGTA_HUMAN (3-140): 2.4e-33: 126: 29.71
+	Hs
		213542 IRF5_HUMAN (2-297): 2.67e-54: 186: 24.05		SGTA_HUMAN (3-140): 2.4e-33: 126: 29.71
+	Hs
		183119 IRF4_HUMAN (7-207): 5.79e-56: 189: 27.36		KDM6A_HUMAN (25-206): 2.59e-10: 63.1: 13.02