HitPredict

Interactor 1: MLRV (P10916)
Myosin regulatory light chain 2, ventricular/cardiac muscle isoform (MLC-2) (MLC-2v) (Cardiac myosin light chain 2) (Myosin light chain 2, slow skeletal/ventricular muscle isoform) (MLC-2s/v) (Ventricular myosin light chain 2)
Gene: MYL2

Interactor 2: LRSM1 (Q6UWE0)
E3 ubiquitin-protein ligase LRSAM1 (EC 2.3.2.27) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (RING-type E3 ubiquitin transferase LRSAM1) (Tsg101-associated ligase) (hTAL)
Gene: LRSAM1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.60	0.457

Property	Details
Experiments	16169070
Identification Methods	two hybrid pooling approach
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 166 Hs			1 723
+	Hs
		483956 CALM1_HUMAN (12-89): 1.76e-10: 57.9: 23.46		LRCH3_HUMAN (11-433): 1.03e-53: 199: 19.38
+	Hs
		484034 CALM2_HUMAN (12-89): 1.76e-10: 57.9: 23.46		LRCH3_HUMAN (11-433): 1.03e-53: 199: 19.38
+	Hs
		484181 CALM3_HUMAN (12-89): 1.76e-10: 57.9: 23.46		LRCH3_HUMAN (11-433): 1.03e-53: 199: 19.38
+	At
		989500 CDPK1_ARATH (56-164): 3.73e-12: 64.9: 12.84		CLV1_ARATH (154-648): 1.44e-40: 162: 10.42
+	At
		99003 CML8_ARATH (86-165): 3.7e-12: 62.1: 13.75		RGI4_ARATH (185-597): 1.72e-38: 155: 12.06
+	At
		99010 CALM7_ARATH (22-89): 4.01e-10: 56.8: 29.58		RGI4_ARATH (185-597): 1.72e-38: 155: 12.06
+	At
		99011 CALM6_ARATH (22-89): 8.47e-10: 56: 29.58		RGI4_ARATH (185-597): 1.72e-38: 155: 12.06
+	Hs
		648644 CALL3_HUMAN (10-89): 1.56e-09: 55.2: 21.69		MFHA1_HUMAN (8-200): 2.08e-34: 143: 28.50
+	Hs
		484011 CALM2_HUMAN (12-89): 1.76e-10: 57.9: 23.46		LRCH2_HUMAN (86-633): 1.4e-30: 130: 14.71
+	Hs
		484142 CALM3_HUMAN (12-89): 1.76e-10: 57.9: 23.46		LRCH2_HUMAN (86-633): 1.4e-30: 130: 14.71
+	Hs
		648524 CALL3_HUMAN (10-89): 1.56e-09: 55.2: 21.69		LRCH2_HUMAN (86-633): 1.4e-30: 130: 14.71
+	Hs
		484224 CALM3_HUMAN (12-89): 1.76e-10: 57.9: 23.46		LRCH1_HUMAN (86-231): 4.12e-26: 116: 19.46
+	Hs
		648641 CALL3_HUMAN (10-89): 1.56e-09: 55.2: 21.69		LRCH1_HUMAN (86-231): 4.12e-26: 116: 19.46
+	At
		188352 CML8_ARATH (86-165): 3.7e-12: 62.1: 13.75		PXC2_ARATH (286-532): 6.34e-19: 93.7: 10.93
+	At
		483157 CALM4_ARATH (22-89): 4.45e-10: 56.8: 29.58		PXC2_ARATH (286-532): 6.34e-19: 93.7: 10.93
+	At
		886620 CALM7_ARATH (22-89): 4.01e-10: 56.8: 29.58		PXC2_ARATH (286-532): 6.34e-19: 93.7: 10.93
+	At
		976683 CALM6_ARATH (22-89): 8.47e-10: 56: 29.58		PXC2_ARATH (286-532): 6.34e-19: 93.7: 10.93
+	At
		1104952 CDPK5_ARATH (99-166): 6.76e-12: 64.1: 16.90		PXL1_ARATH (331-648): 2.97e-15: 82.2: 10.46