HitPredict

Interactor 1: RPA1 (P10964)
DNA-directed RNA polymerase I subunit RPA190 (EC 2.7.7.6) (DNA-directed RNA polymerase I 190 kDa polypeptide) (A190) (DNA-directed RNA polymerase I largest subunit)
Gene: RPA190

Interactor 2: RPAB3 (P20436)
DNA-directed RNA polymerases I, II, and III subunit RPABC3 (RNA polymerases I, II, and III subunit ABC3) (ABC14.4) (ABC14.5) (DNA-directed RNA polymerases I, II, and III 14.5 kDa polypeptide)
Gene: RPB8

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.88 1.00 0.943

The method score is based on:

Property Details
Experiments 11805826, 24307683, 16554755, 16429126, 37968396, 21048197
Identification Methods tandem affinity purification, affinity chromatography technology
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains RNA_pol_Rpb1_3~RNA_pol_Rpb8, RNA_pol_Rpb1_4~RNA_pol_Rpb8, RNA_pol_Rpb1_5~RNA_pol_Rpb8
Common GO terms GO:0001054 - RNA polymerase I activity
GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0005736 - RNA polymerase I complex
GO:0006360 - transcription by RNA polymerase I
and 5 others

more...
Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 1664
Sc

1 146
+ Hs
+ Hs
+ Hs
+ Bt
+ Sp
+ Sc
+ Sc
+ Hs
+ At
+ At

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Last updated: 15 Jul 2024