HitPredict

Interactor 1: RPA1 (P10964)
DNA-directed RNA polymerase I subunit RPA190 (EC 2.7.7.6) (DNA-directed RNA polymerase I 190 kDa polypeptide) (A190) (DNA-directed RNA polymerase I largest subunit)
Gene: RPA190

Interactor 2: DOA1 (P36037)
Protein DOA1 (Degradation of alpha protein 1) (Ubiquitin fusion degradation protein 3)
Gene: DOA1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.57	0.60	0.588

Property	Details
Experiments	11805826, 16429126
Identification Methods	tandem affinity purification, affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1664 Sc			1 715
+	Hs
		317184 RPA1_HUMAN (1-1660): 0: 1572: 35.59		FBW1B_HUMAN (99-329): 3.03e-45: 171: 23.53
+	Hs
		317142 RPA1_HUMAN (1-1660): 0: 1572: 35.59		FBXW7_HUMAN (205-534): 1.17e-40: 160: 14.63
+	Hs
		625108 RPB1_HUMAN (9-1662): 0: 1406: 22.39		FBW1A_HUMAN (124-459): 4.96e-44: 169: 15.79
+	Hs
		624985 RPB1_HUMAN (9-1662): 0: 1406: 22.39		FBXW7_HUMAN (205-534): 1.17e-40: 160: 14.63
+	Mm
		444958 RPB1_MOUSE (9-1662): 0: 1406: 22.39		WDR5_MOUSE (2-82): 7.4e-13: 72.3: 12.64
+	Sc
		375370 RPB1_YEAST (9-1661): 0: 1195: 21.76		TAF5_YEAST (89-302): 5.91e-19: 93.6: 32.74
+	Sc
		375599 RPC1_YEAST (7-237): 1.65e-48: 192: 17.72		DOA1_YEAST (1-715): 0: 540: 100.00