HitPredict

Interactor 1: ACT1 (P10987)
Actin-5C (EC 3.6.4.-)
Gene: Act5C

Interactor 2: LASP1 (Q8I7C3)
LIM and SH3 domain protein Lasp
Gene: Lasp

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	25113030
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0007291 - sperm individualization
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 376 Dm			1 657
+	Dm
		501447 ACT5_DROME (1-376): 0: 605: 96.81		LASP1_DROME (1-657): 2.76e-103: 330: 100.00
+	Dm
		361146 ACT2_DROME (1-376): 0: 604: 99.47		LASP1_DROME (1-657): 2.76e-103: 330: 100.00
+	Dm
		862562 ACT3_DROME (1-376): 0: 603: 96.28		LASP1_DROME (1-657): 2.76e-103: 330: 100.00
+	Dm
		950121 ACT6_DROME (1-376): 0: 603: 96.01		LASP1_DROME (1-657): 2.76e-103: 330: 100.00
+	Dm
		361184 ACT4_DROME (1-376): 0: 598: 95.75		LASP1_DROME (1-657): 2.76e-103: 330: 100.00
+	Hs
		596202 ACTB_HUMAN (1-376): 0: 603: 97.61		NEBU_HUMAN (68-655): 1.48e-52: 198: 19.43
+	Hs
		596210 ACTH_HUMAN (1-376): 0: 598: 94.15		NEBU_HUMAN (68-655): 1.48e-52: 198: 19.43
+	Hs
		933013 ACTS_HUMAN (2-376): 0: 598: 93.33		NRAP_HUMAN (3-543): 6.14e-49: 187: 16.81
+	Hs
		282322 ACTB_HUMAN (1-376): 0: 603: 97.61		NEBL_HUMAN (68-653): 1.79e-40: 161: 18.00
+	Hs
		930053 ACTG_HUMAN (3-376): 0: 603: 98.13		PACN2_HUMAN (182-655): 1.83e-37: 147: 11.45
+	Hs
		150545 ACTB_HUMAN (1-376): 0: 603: 97.61		ABLM1_HUMAN (2-513): 5.92e-34: 140: 11.69
+	Hs
		150554 ACTG_HUMAN (3-376): 0: 603: 98.13		ABLM1_HUMAN (2-513): 5.92e-34: 140: 11.69
+	Hs
		235496 ACTS_HUMAN (2-376): 0: 598: 93.33		VINEX_HUMAN (524-652): 1.61e-33: 138: 26.36
+	Hs
		891770 ACTB_HUMAN (1-376): 0: 603: 97.61		LASP1_HUMAN (538-653): 3.97e-23: 101: 35.66
+	Hs
		929877 ACTG_HUMAN (3-376): 0: 603: 98.13		CSRP2_HUMAN (4-101): 1.32e-17: 83.5: 21.01
+	Hs
		300997 ACTC_HUMAN (2-376): 0: 598: 94.40		ABLM3_HUMAN (5-591): 4.23e-12: 71.3: 8.42
+	Hs
		300998 ACTS_HUMAN (2-376): 0: 598: 93.33		ABLM3_HUMAN (5-591): 4.23e-12: 71.3: 8.42
+	Hs
		891821 ACTB_HUMAN (1-376): 0: 603: 97.61		SH319_HUMAN (596-653): 3.46e-10: 65.3: 43.10
+	Hs
		892005 ACTB_HUMAN (1-376): 0: 603: 97.61		SRBS1_HUMAN (593-653): 4.9e-09: 61.9: 32.79
+	Hs
		932362 ACTC_HUMAN (2-376): 0: 598: 94.40		SRBS1_HUMAN (593-653): 4.9e-09: 61.9: 32.79