HitPredict

Interactor 1: ACT1 (P10987)
Actin-5C (EC 3.6.4.-)
Gene: Act5C

Interactor 2: Q9W4A9 (Q9W4A9)
Rho GTPase activating protein at 5A, isoform A
Gene: RhoGAP5A

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	22036573
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Actin~RhoGAP
Common GO terms	-
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 376 Dm			1 494
+	Hs
		1122443 ACTBL_HUMAN (1-376): 0: 733: 90.69		RHG12_HUMAN (283-492): 3.87e-59: 210: 27.57
+	Hs
		112131 ACTG_HUMAN (3-376): 0: 603: 98.13		M0R0P8_HUMAN (2-487): 2.98e-85: 289: 19.48
+	Hs
		891744 ACTB_HUMAN (1-376): 0: 603: 97.61		MYO9B_HUMAN (2-487): 2.98e-85: 289: 19.48
+	Hs
		929850 ACTG_HUMAN (3-376): 0: 603: 98.13		MYO9B_HUMAN (2-487): 2.98e-85: 289: 19.48
+	Hs
		891856 ACTB_HUMAN (1-376): 0: 603: 97.61		RHG27_HUMAN (2-492): 9e-81: 270: 19.19
+	Hs
		929907 ACTG_HUMAN (3-376): 0: 603: 98.13		RHG27_HUMAN (2-492): 9e-81: 270: 19.19
+	Hs
		891826 ACTB_HUMAN (1-376): 0: 603: 97.61		RHG21_HUMAN (144-493): 3.18e-69: 242: 22.07
+	Hs
		891880 ACTB_HUMAN (1-376): 0: 603: 97.61		RHG12_HUMAN (283-492): 3.87e-59: 210: 27.57
+	Hs
		929916 ACTG_HUMAN (3-376): 0: 603: 98.13		RHG12_HUMAN (283-492): 3.87e-59: 210: 27.57
+	Hs
		64678 ACTB_HUMAN (1-376): 0: 603: 97.61		RHG32_HUMAN (247-493): 1.61e-57: 208: 23.51
+	Hs
		64690 ACTG_HUMAN (3-376): 0: 603: 98.13		RHG32_HUMAN (247-493): 1.61e-57: 208: 23.51
+	Hs
		892060 ACTB_HUMAN (1-376): 0: 603: 97.61		RHG35_HUMAN (302-464): 6.65e-24: 107: 33.74
+	Hs
		932401 ACTC_HUMAN (2-376): 0: 598: 94.40		RHG35_HUMAN (302-464): 6.65e-24: 107: 33.74
+	Hs
		891894 ACTB_HUMAN (1-376): 0: 603: 97.61		RHG24_HUMAN (300-464): 3.17e-21: 99.4: 34.12
+	Hs
		929924 ACTG_HUMAN (3-376): 0: 603: 98.13		RHG24_HUMAN (300-464): 3.17e-21: 99.4: 34.12