HitPredict

Interactor 1: ACT (P10989)
Actin (EC 3.6.4.-)
Gene: act1

Interactor 2: CAP (P36621)
Adenylyl cyclase-associated protein (CAP)
Gene: cap1

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.80	0.637

Property	Details
Experiments	26542710
Identification Methods	two hybrid, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Actin~CAP_C
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 375 Sp			1 551
+	Hs
		768462 ACTB_HUMAN (1-375): 0: 598: 90.40		CAP2_HUMAN (68-549): 0: 614: 33.95
+	Hs
		768466 ACTG_HUMAN (1-375): 0: 598: 91.47		CAP2_HUMAN (68-549): 0: 614: 33.95
+	Hs
		768474 Q1KLZ0_HUMAN (1-375): 0: 598: 90.40		CAP2_HUMAN (68-549): 0: 614: 33.95
+	Hs
		768467 ACTC_HUMAN (2-375): 0: 588: 89.04		CAP2_HUMAN (68-549): 0: 614: 33.95
+	Hs
		768468 ACTS_HUMAN (2-375): 0: 588: 89.04		CAP2_HUMAN (68-549): 0: 614: 33.95
+	Hs
		768465 ACTA_HUMAN (2-375): 0: 587: 89.04		CAP2_HUMAN (68-549): 0: 614: 33.95
+	Hs
		891700 ACTB_HUMAN (1-375): 0: 598: 90.40		CAP1_HUMAN (68-549): 0: 586: 32.17
+	Hs
		929826 ACTG_HUMAN (1-375): 0: 598: 91.47		CAP1_HUMAN (68-549): 0: 586: 32.17
+	Hs
		932109 ACTC_HUMAN (2-375): 0: 588: 89.04		CAP1_HUMAN (68-549): 0: 586: 32.17
+	Hs
		932956 ACTS_HUMAN (2-375): 0: 588: 89.04		CAP1_HUMAN (68-549): 0: 586: 32.17
+	Hs
		915363 ACTA_HUMAN (2-375): 0: 587: 89.04		CAP1_HUMAN (68-549): 0: 586: 32.17
+	Sc
		568336 ACT_YEAST (1-375): 0: 588: 89.60		CAP_YEAST (11-550): 0: 553: 33.27
+	Dm
		501544 ACT1_DROME (2-375): 0: 593: 90.91		Q9VPX7_DROME (105-540): 0: 532: 35.93
+	Dm
		361155 ACT2_DROME (2-375): 0: 592: 90.91		Q9VPX7_DROME (105-540): 0: 532: 35.93
+	Dm
		501500 ACT1_DROME (2-375): 0: 593: 90.91		Q7KN55_DROME (105-540): 0: 529: 35.93
+	Dm
		501456 ACT5_DROME (2-375): 0: 593: 90.11		Q9VPX6_DROME (105-540): 1.12e-169: 502: 35.93
+	Dm
		501543 ACT1_DROME (2-375): 0: 593: 90.91		Q9VPX6_DROME (105-540): 1.12e-169: 502: 35.93
+	Dm
		361154 ACT2_DROME (2-375): 0: 592: 90.91		Q9VPX6_DROME (105-540): 1.12e-169: 502: 35.93
+	Dm
		862578 ACT3_DROME (2-375): 0: 591: 89.31		Q9VPX6_DROME (105-540): 1.12e-169: 502: 35.93
+	Dm
		950127 ACT6_DROME (2-375): 0: 590: 89.31		Q9VPX6_DROME (105-540): 1.12e-169: 502: 35.93