HitPredict

Interactor 1: ACT (P10989)
Actin (EC 3.6.4.-)
Gene: act1

Interactor 2: TPM (Q02088)
Tropomyosin
Gene: cdc8

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.70	1.00	0.840

Property	Details
Experiments	27501521, 9765059, 28282023
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Actin~Tropomyosin
Common GO terms	GO:0005884 - actin filament GO:0030479 - actin cortical patch GO:0032153 - cell division site GO:0043332 - mating projection tip
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 375 Sp			1 161
+	Hs
		891932 ACTB_HUMAN (1-375): 0: 598: 90.40		CTTB2_HUMAN (3-161): 3.05e-49: 171: 20.86
+	Sc
		772954 ACT_YEAST (1-375): 0: 588: 89.60		TPM2_YEAST (1-161): 2.68e-34: 119: 34.16
+	Sc
		568129 ACT_YEAST (1-375): 0: 588: 89.60		TPM1_YEAST (1-161): 7.48e-27: 101: 30.15
+	Hs
		892081 ACTB_HUMAN (1-375): 0: 598: 90.40		CT2NL_HUMAN (11-161): 1.06e-19: 86.6: 17.42
+	Hs
		787883 ACTB_HUMAN (1-375): 0: 598: 90.40		EPS15_HUMAN (10-161): 2.15e-10: 60: 15.13