HitPredict

Interactor 1: BIP (P11021)
Endoplasmic reticulum chaperone BiP (EC 3.6.4.10) (78 kDa glucose-regulated protein) (GRP-78) (Binding-immunoglobulin protein) (BiP) (Heat shock protein 70 family protein 5) (HSP70 family protein 5) (Heat shock protein family A member 5) (Immunoglobulin heavy chain-binding protein)
Gene: HSPA5

Interactor 2: DNMT1 (P26358)
DNA (cytosine-5)-methyltransferase 1 (Dnmt1) (EC 2.1.1.37) (CXXC-type zinc finger protein 9) (DNA methyltransferase HsaI) (DNA MTase HsaI) (M.HsaI) (MCMT)
Gene: DNMT1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	21745816
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 654 Hs			1 1616
+	Hs
		503473 HSP7C_HUMAN (26-637): 0: 916: 66.02		DNMT1_HUMAN (1-1616): 0: 1717: 100.00
+	Xl
		365426 HSP70_XENLA (25-654): 0: 907: 60.96		P79922_XENLA (126-1616): 0: 1502: 70.07
+	Xl
		945599 BIP_XENLA (1-654): 0: 907: 92.10		P79922_XENLA (126-1616): 0: 1502: 70.07
+	Hs
		504974 HSP7C_HUMAN (26-637): 0: 916: 66.02		SMC3_HUMAN (112-523): 4.15e-40: 164: 12.53
+	Hs
		504619 HSP7C_HUMAN (26-637): 0: 916: 66.02		MINT_HUMAN (5-706): 1.98e-35: 150: 12.71
+	Hs
		871747 HSP72_HUMAN (25-636): 0: 905: 64.51		MINT_HUMAN (5-706): 1.98e-35: 150: 12.71
+	Hs
		504250 HSP7C_HUMAN (26-637): 0: 916: 66.02		NIPBL_HUMAN (4-361): 1.81e-13: 78.5: 14.14