HitPredict

Interactor 1: BIP (P11021)
Endoplasmic reticulum chaperone BiP (EC 3.6.4.10) (78 kDa glucose-regulated protein) (GRP-78) (Binding-immunoglobulin protein) (BiP) (Heat shock protein 70 family protein 5) (HSP70 family protein 5) (Heat shock protein family A member 5) (Immunoglobulin heavy chain-binding protein)
Gene: HSPA5

Interactor 2: RFA1 (P27694)
Replication protein A 70 kDa DNA-binding subunit (RP-A p70) (Replication factor A protein 1) (RF-A protein 1) (Single-stranded DNA-binding protein) [Cleaved into: Replication protein A 70 kDa DNA-binding subunit, N-terminally processed]
Gene: RPA1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	37827155, 24332808
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 654 Hs			1 616
+	Hs
		503483 HSP7C_HUMAN (26-637): 0: 916: 66.02		RFA1_HUMAN (1-616): 0: 781: 100.00
+	Hs
		564011 HSP76_HUMAN (25-635): 0: 915: 62.54		RFA1_HUMAN (1-616): 0: 781: 100.00
+	Sc
		560566 BIP_YEAST (22-638): 0: 798: 68.82		RFA1_YEAST (4-615): 0: 596: 31.69