Interactor 1: BIP (P11021)
Endoplasmic reticulum chaperone BiP (EC 3.6.4.10) (78 kDa glucose-regulated protein) (GRP-78) (Binding-immunoglobulin protein) (BiP) (Heat shock protein 70 family protein 5) (HSP70 family protein 5) (Heat shock protein family A member 5) (Immunoglobulin heavy chain-binding protein)
Gene: HSPA5
Interactor 2: HSP74 (P34932)
Heat shock 70 kDa protein 4 (HSP70RY) (Heat shock 70-related protein APG-2) (Heat shock protein family H member 2)
Gene: HSPA4
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.47 | 1.00 | 0.691 |
The method score is based on:
Property | Details |
---|---|
Experiments | 35271311 |
Identification Methods | affinity chromatography technology, anti tag coimmunoprecipitation |
Interaction Type | physical association, association |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | HSP70~HSP70 |
Common GO terms | GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005739 - mitochondrion GO:0005829 - cytosol GO:0070062 - extracellular exosome and 1 others more... |
Homologous interactions | 18 |
Homologous interactions
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024