HitPredict

Interactor 1: BIP (P11021)
Endoplasmic reticulum chaperone BiP (EC 3.6.4.10) (78 kDa glucose-regulated protein) (GRP-78) (Binding-immunoglobulin protein) (BiP) (Heat shock protein 70 family protein 5) (HSP70 family protein 5) (Heat shock protein family A member 5) (Immunoglobulin heavy chain-binding protein)
Gene: HSPA5

Interactor 2: MYH10 (P35580)
Myosin-10 (Cellular myosin heavy chain, type B) (Myosin heavy chain 10) (Myosin heavy chain, non-muscle IIb) (Non-muscle myosin heavy chain B) (NMMHC-B) (Non-muscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB)
Gene: MYH10

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	30021884, 36042349
Identification Methods	proximity labelling technology, affinity chromatography technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0030496 - midbody and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1 654 Hs			1 1976
+	Hs
		501755 BIP_HUMAN (19-654): 0: 914: 100.00		MYH9_HUMAN (877-1976): 1.43e-64: 246: 17.95
+	Hs
		64578 HSP7C_HUMAN (26-637): 0: 916: 66.02		MYH7B_HUMAN (1184-1976): 1.23e-40: 167: 15.67