HitPredict

Interactor 1: BIP (P11021)
Endoplasmic reticulum chaperone BiP (EC 3.6.4.10) (78 kDa glucose-regulated protein) (GRP-78) (Binding-immunoglobulin protein) (BiP) (Heat shock protein 70 family protein 5) (HSP70 family protein 5) (Heat shock protein family A member 5) (Immunoglobulin heavy chain-binding protein)
Gene: HSPA5

Interactor 2: I12R1 (P42701)
Interleukin-12 receptor subunit beta-1 (IL-12 receptor subunit beta-1) (IL-12R subunit beta-1) (IL-12R-beta-1) (IL-12RB1) (IL-12 receptor beta component) (CD antigen CD212)
Gene: IL12RB1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 654 Hs			1 662
+	Hs
		265748 BIP_HUMAN (19-654): 0: 914: 100.00		CRLF1_HUMAN (44-239): 6.07e-41: 156: 18.72
+	Hs
		489911 HS71L_HUMAN (24-647): 0: 922: 63.16		PTPRF_HUMAN (288-660): 2.98e-20: 98.2: 11.97
+	Hs
		489889 HSP7C_HUMAN (26-637): 0: 916: 66.02		PTPRF_HUMAN (288-660): 2.98e-20: 98.2: 11.97
+	Hs
		489888 BIP_HUMAN (19-654): 0: 914: 100.00		PTPRF_HUMAN (288-660): 2.98e-20: 98.2: 11.97
+	Hs
		504482 HSP7C_HUMAN (26-637): 0: 916: 66.02		TITIN_HUMAN (41-158): 1.09e-09: 64.3: 9.09