HitPredict

Interactor 1: BIP (P11021)
Endoplasmic reticulum chaperone BiP (EC 3.6.4.10) (78 kDa glucose-regulated protein) (GRP-78) (Binding-immunoglobulin protein) (BiP) (Heat shock protein 70 family protein 5) (HSP70 family protein 5) (Heat shock protein family A member 5) (Immunoglobulin heavy chain-binding protein)
Gene: HSPA5

Interactor 2: UB2R1 (P49427)
Ubiquitin-conjugating enzyme E2 R1 (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme R1) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme R1) (Ubiquitin-conjugating enzyme E2-32 kDa complementing) (Ubiquitin-conjugating enzyme E2-CDC34) (Ubiquitin-protein ligase R1)
Gene: CDC34

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29564676
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 654 Hs			1 236
+	Hs
		503677 HSP7C_HUMAN (26-637): 0: 916: 66.02		UB2R1_HUMAN (1-236): 1.98e-95: 280: 100.00
+	Hs
		564035 HSP76_HUMAN (25-635): 0: 915: 62.54		UB2R1_HUMAN (1-236): 1.98e-95: 280: 100.00
+	Hs
		827884 HSP72_HUMAN (25-636): 0: 905: 64.51		UB2R1_HUMAN (1-236): 1.98e-95: 280: 100.00
+	Hs
		502255 BIP_HUMAN (19-654): 0: 914: 100.00		UB2R2_HUMAN (1-203): 5.2e-79: 238: 84.73
+	Hs
		828965 HSP72_HUMAN (25-636): 0: 905: 64.51		UBE2A_HUMAN (9-157): 1.04e-26: 102: 38.26