HitPredict

Interactor 1: BIP (P11021)
Endoplasmic reticulum chaperone BiP (EC 3.6.4.10) (78 kDa glucose-regulated protein) (GRP-78) (Binding-immunoglobulin protein) (BiP) (Heat shock protein 70 family protein 5) (HSP70 family protein 5) (Heat shock protein family A member 5) (Immunoglobulin heavy chain-binding protein)
Gene: HSPA5

Interactor 2: LAMB2 (P55268)
Laminin subunit beta-2 (Laminin B1s chain) (Laminin-11 subunit beta) (Laminin-14 subunit beta) (Laminin-15 subunit beta) (Laminin-3 subunit beta) (Laminin-4 subunit beta) (Laminin-7 subunit beta) (Laminin-9 subunit beta) (S-laminin subunit beta) (S-LAM beta)
Gene: LAMB2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005788 - endoplasmic reticulum lumen GO:0070062 - extracellular exosome
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 654 Hs			1 1798
+	Hs
		502805 HSP7C_HUMAN (26-637): 0: 916: 66.02		LAMC1_HUMAN (892-1798): 4.14e-48: 192: 15.39
+	Hs
		501606 BIP_HUMAN (19-654): 0: 914: 100.00		LAMC1_HUMAN (892-1798): 4.14e-48: 192: 15.39
+	Hs
		433114 BIP_HUMAN (19-654): 0: 914: 100.00		LAMB1_HUMAN (874-1798): 1.4e-42: 173: 14.84
+	Hs
		502002 BIP_HUMAN (19-654): 0: 914: 100.00		NOTC2_HUMAN (295-686): 1.81e-25: 118: 13.07
+	Hs
		564212 HSP76_HUMAN (25-635): 0: 915: 62.54		NTNG1_HUMAN (783-951): 4.86e-12: 72.7: 18.61
+	Hs
		501701 BIP_HUMAN (19-654): 0: 914: 100.00		LAMA1_HUMAN (541-742): 5.94e-10: 66.9: 9.80