Interactor 1: BIP (P11021)
Endoplasmic reticulum chaperone BiP (EC 3.6.4.10) (78 kDa glucose-regulated protein) (GRP-78) (Binding-immunoglobulin protein) (BiP) (Heat shock protein 70 family protein 5) (HSP70 family protein 5) (Heat shock protein family A member 5) (Immunoglobulin heavy chain-binding protein)
Gene: HSPA5

Interactor 2: SPART (Q8N0X7)
Spartin (Spastic paraplegia 20 protein) (Trans-activated by hepatitis C virus core protein 1)
Gene: SPART

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.64 0.60 0.621

The method score is based on:

Property Details
Experiments 34349018, 19765186
Identification Methods cross-linking study, affinity chromatography technology, tandem affinity purification, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0030496 - midbody
GO:0031625 - ubiquitin protein ligase binding
and 1 others

more...

Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 654
Hs

1 666
+ Rn
+ At
+ Hs
+ Hs
+ Hs
+ Sp
+ Sc

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Last updated: 15 Jul 2024