Interactor 1: BIP (P11021)
Endoplasmic reticulum chaperone BiP (EC 3.6.4.10) (78 kDa glucose-regulated protein) (GRP-78) (Binding-immunoglobulin protein) (BiP) (Heat shock protein 70 family protein 5) (HSP70 family protein 5) (Heat shock protein family A member 5) (Immunoglobulin heavy chain-binding protein)
Gene: HSPA5

Interactor 2: PA2G4 (Q9UQ80)
Proliferation-associated protein 2G4 (Cell cycle protein p38-2G4 homolog) (hG4-1) (ErbB3-binding protein 1)
Gene: PA2G4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.70 0.60 0.650

The method score is based on:

Property Details
Experiments 30021884, 34349018, 35235311
Identification Methods proximity labelling technology, cross-linking study
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0016020 - membrane
GO:0031625 - ubiquitin protein ligase binding
GO:0043066 - negative regulation of apoptotic process
and 1 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 654
Hs

1 394
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024