HitPredict

Interactor 1: LAMC1 (P11047)
Laminin subunit gamma-1 (Laminin B2 chain) (Laminin-1 subunit gamma) (Laminin-10 subunit gamma) (Laminin-11 subunit gamma) (Laminin-2 subunit gamma) (Laminin-3 subunit gamma) (Laminin-4 subunit gamma) (Laminin-6 subunit gamma) (Laminin-7 subunit gamma) (Laminin-8 subunit gamma) (Laminin-9 subunit gamma) (S-laminin subunit gamma) (S-LAM gamma)
Gene: LAMC1

Interactor 2: LGR4 (Q9BXB1)
Leucine-rich repeat-containing G-protein coupled receptor 4 (G-protein coupled receptor 48)
Gene: LGR4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	24639526
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Laminin_N~LRR_8
Common GO terms	-
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1609 Hs			1 951
+	Hs
		502811 LAMC1_HUMAN (1-1609): 0: 1092: 100.00		TSHR_HUMAN (31-302): 4.28e-16: 85: 20.89
+	Hs
		433119 LAMB1_HUMAN (21-1561): 0: 668: 20.81		TSHR_HUMAN (31-302): 4.28e-16: 85: 20.89
+	Hs
		296652 NOTC2_HUMAN (267-880): 2.73e-47: 189: 12.77		SLIT2_HUMAN (57-481): 8.54e-40: 162: 20.08
+	Hs
		1335626 NOTC3_HUMAN (266-561): 3.73e-21: 103: 15.25		RXFP1_HUMAN (28-319): 2.69e-53: 201: 29.59
+	Dm
		422776 NOTCH_DROME (760-1122): 4.9e-29: 129: 14.29		TOLL7_DROME (29-190): 1.33e-09: 64.3: 26.47
+	Hs
		560512 LAMA3_HUMAN (463-642): 1.28e-13: 78.7: 12.16		TSHR_HUMAN (31-302): 4.28e-16: 85: 20.89
+	Hs
		560493 LAMB2_HUMAN (1194-1543): 3.11e-10: 67.6: 12.57		TSHR_HUMAN (31-302): 4.28e-16: 85: 20.89