HitPredict

Interactor 1: TSN11 (A1L157)
Tetraspanin-11 (Tspan-11)
Gene: TSPAN11

Interactor 2: ITB1 (P05556)
Integrin beta-1 (Fibronectin receptor subunit beta) (Glycoprotein IIa) (GPIIA) (VLA-4 subunit beta) (CD antigen CD29)
Gene: ITGB1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 253 Hs			1 798
+	Hs
		403820 CD151_HUMAN (1-253): 3.03e-75: 230: 56.13		ITB1_HUMAN (1-798): 0: 794: 100.00
+	Hs
		403847 TSN5_HUMAN (5-250): 2.75e-65: 205: 25.86		ITB1_HUMAN (1-798): 0: 794: 100.00
+	Hs
		403813 TSN7_HUMAN (5-253): 4.61e-64: 202: 26.98		ITB1_HUMAN (1-798): 0: 794: 100.00
+	Hs
		403744 CD63_HUMAN (10-252): 4.56e-58: 186: 24.28		ITB1_HUMAN (1-798): 0: 794: 100.00
+	Hs
		403839 CD81_HUMAN (10-251): 1.73e-54: 177: 24.50		ITB1_HUMAN (1-798): 0: 794: 100.00
+	Hs
		326008 TSN15_HUMAN (15-249): 3.56e-50: 167: 26.72		ITB1_HUMAN (1-798): 0: 794: 100.00
+	Hs
		156129 TSN4_HUMAN (12-248): 2.31e-49: 164: 30.80		ITB1_HUMAN (1-798): 0: 794: 100.00
+	Hs
		403784 CD9_HUMAN (10-251): 1.12e-48: 162: 25.51		ITB1_HUMAN (1-798): 0: 794: 100.00
+	Hs
		326265 TSN12_HUMAN (13-244): 3.83e-46: 157: 29.56		ITB1_HUMAN (1-798): 0: 794: 100.00
+	Hs
		396617 CD151_HUMAN (1-253): 3.03e-75: 230: 56.13		ITB2_HUMAN (23-796): 0: 658: 45.50
+	Hs
		574512 CD81_HUMAN (10-251): 1.73e-54: 177: 24.50		ITB5_HUMAN (19-792): 0: 660: 42.64
+	Hs
		276300 UPK1B_HUMAN (8-249): 6.25e-47: 158: 19.84		ITB2_HUMAN (23-796): 0: 658: 45.50
+	Hs
		556422 CD151_HUMAN (1-253): 3.03e-75: 230: 56.13		ITB4_HUMAN (11-727): 0: 566: 33.65
+	Hs
		905571 TSN5_HUMAN (5-250): 2.75e-65: 205: 25.86		TEN3_HUMAN (520-739): 8e-38: 155: 19.33
+	Hs
		326243 TSN15_HUMAN (15-249): 3.56e-50: 167: 26.72		TEN3_HUMAN (520-739): 8e-38: 155: 19.33
+	Hs
		602289 CD9_HUMAN (10-251): 1.12e-48: 162: 25.51		TEN3_HUMAN (520-739): 8e-38: 155: 19.33
+	Hs
		905569 TSN5_HUMAN (5-250): 2.75e-65: 205: 25.86		TEN2_HUMAN (597-739): 2.8e-16: 85.9: 18.06
+	Hs
		101394 CD81_HUMAN (10-251): 1.73e-54: 177: 24.50		F8VNQ3_HUMAN (597-739): 1.67e-16: 86.7: 18.06
+	Hs
		326236 TSN15_HUMAN (15-249): 3.56e-50: 167: 26.72		TEN2_HUMAN (597-739): 2.8e-16: 85.9: 18.06
+	Hs
		602286 CD9_HUMAN (10-251): 1.12e-48: 162: 25.51		TEN2_HUMAN (597-739): 2.8e-16: 85.9: 18.06