HitPredict

Interactor 1: U2QL1 (A1L167)
Ubiquitin-conjugating enzyme E2Q-like protein 1 (EC 2.3.2.23) (E2Q-like ubiquitin-conjugating enzyme 1)
Gene: UBE2QL1

Interactor 2: FBXW7 (Q969H0)
F-box/WD repeat-containing protein 7 (Archipelago homolog) (hAgo) (F-box and WD-40 domain-containing protein 7) (F-box protein FBX30) (SEL-10) (hCdc4)
Gene: FBXW7

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	24000165
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	UQ_con~WD40
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 161 Hs			1 707
+	Hs
		896507 UBE2N_HUMAN (1-151): 5.36e-53: 167: 17.76		FBXW7_HUMAN (1-707): 0: 571: 100.00
+	Hs
		849435 UB2D1_HUMAN (2-150): 3.48e-58: 179: 20.00		TBL1R_HUMAN (251-570): 8.42e-66: 228: 18.58
+	Hs
		1282344 UB2E3_HUMAN (2-149): 1.4e-53: 170: 19.46		TBL1R_HUMAN (251-570): 8.42e-66: 228: 18.58
+	Sc
		539467 UBC3_YEAST (1-114): 6.05e-36: 127: 25.00		MET30_YEAST (447-706): 5.61e-59: 212: 25.24
+	Hs
		1163056 UB2D4_HUMAN (2-150): 9.54e-61: 186: 20.67		TRAF7_HUMAN (492-703): 4.9e-16: 84: 31.34
+	Hs
		919901 UB2D2_HUMAN (2-150): 3.17e-59: 182: 20.67		FBXW2_HUMAN (574-692): 2.05e-17: 87.3: 26.89
+	Hs
		919755 UB2D2_HUMAN (2-150): 3.17e-59: 182: 20.67		TRAF7_HUMAN (492-703): 4.9e-16: 84: 31.34
+	Hs
		849344 UB2D1_HUMAN (2-150): 3.48e-58: 179: 20.00		TRAF7_HUMAN (492-703): 4.9e-16: 84: 31.34
+	Sc
		431114 UBC3_YEAST (1-114): 6.05e-36: 127: 25.00		CDC4_YEAST (536-707): 7.01e-30: 128: 28.57
+	Dm
		218245 UBCD1_DROME (2-150): 2.96e-59: 182: 21.33		O44382_DROME (607-705): 1.7e-12: 72.4: 22.00
+	Hs
		919912 UB2D2_HUMAN (2-150): 3.17e-59: 182: 20.67		FBW1A_HUMAN (614-705): 2.9e-12: 72: 26.09
+	Hs
		895959 UB2D3_HUMAN (2-150): 1.62e-58: 180: 20.67		FBW1A_HUMAN (614-705): 2.9e-12: 72: 26.09
+	Hs
		849492 UB2D1_HUMAN (2-150): 3.48e-58: 179: 20.00		FBW1A_HUMAN (614-705): 2.9e-12: 72: 26.09
+	Hs
		895947 UB2D3_HUMAN (2-150): 1.62e-58: 180: 20.67		FBW1B_HUMAN (614-705): 7.05e-12: 70.5: 25.00