HitPredict

Interactor 1: ARF1 (P11076)
ADP-ribosylation factor 1 (EC 3.6.5.2)
Gene: ARF1

Interactor 2: COPB2 (P41811)
Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP)
Gene: SEC27

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.69	0.60	0.646

Property	Details
Experiments	36811888, 15356266, 22304919
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0006886 - intracellular protein transport GO:0006888 - endoplasmic reticulum to Golgi vesicle-mediated transport
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 181 Sc			1 889
+	Hs
		725412 ARF6_HUMAN (5-179): 5.38e-71: 214: 65.71		COPB2_HUMAN (1-882): 0: 608: 42.26
+	Hs
		725418 ARF5_HUMAN (1-180): 1.01e-68: 208: 69.44		COPB2_HUMAN (1-882): 0: 608: 42.26
+	Hs
		574610 ARF4_HUMAN (1-180): 3.03e-66: 202: 72.22		COPB2_HUMAN (1-882): 0: 608: 42.26
+	Dm
		248478 ARF4_DROME (1-180): 4.46e-73: 219: 72.78		COPB2_DROME (1-889): 0: 587: 40.31
+	Dm
		248479 ARF1_DROME (1-181): 5.18e-68: 206: 78.45		COPB2_DROME (1-889): 0: 587: 40.31
+	Sc
		503120 ARF1_YEAST (1-181): 6.31e-68: 206: 100.00		COPA_YEAST (3-887): 8.6e-161: 503: 20.34
+	Dm
		778388 ARF4_DROME (1-180): 4.46e-73: 219: 72.78		Q9W0B8_DROME (2-288): 2.44e-50: 194: 17.96
+	Dm
		897483 ARF1_DROME (1-181): 5.18e-68: 206: 78.45		Q9W0B8_DROME (2-288): 2.44e-50: 194: 17.96
+	Hs
		903100 RAB1A_HUMAN (5-180): 3.95e-67: 205: 20.99		WDR5_HUMAN (342-624): 6.55e-49: 178: 11.11
+	Hs
		903508 RAB1B_HUMAN (5-180): 7.15e-67: 204: 20.99		WDR5_HUMAN (342-624): 6.55e-49: 178: 11.11
+	Hs
		574641 ARF4_HUMAN (1-180): 3.03e-66: 202: 72.22		WDR5_HUMAN (342-624): 6.55e-49: 178: 11.11
+	Hs
		863404 ARF5_HUMAN (1-180): 1.01e-68: 208: 69.44		COPA_HUMAN (2-418): 5.05e-37: 152: 13.73