HitPredict

Interactor 1: ARF1 (P11076)
ADP-ribosylation factor 1 (EC 3.6.5.2)
Gene: ARF1

Interactor 2: COPA (P53622)
Coatomer subunit alpha (Alpha-coat protein) (Alpha-COP) (Retrieval from endoplasmic reticulum protein 1) (Secretory protein 22) (Suppressor of osmo-sensitivity 1)
Gene: COP1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	15356266, 33401608
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0006886 - intracellular protein transport GO:0006888 - endoplasmic reticulum to Golgi vesicle-mediated transport
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 181 Sc			1 1201
+	Hs
		863404 ARF5_HUMAN (1-180): 1.01e-68: 208: 69.44		COPA_HUMAN (3-1199): 0: 1078: 42.67
+	Hs
		725412 ARF6_HUMAN (5-179): 5.38e-71: 214: 65.71		COPB2_HUMAN (1-909): 0: 562: 20.65
+	Hs
		725418 ARF5_HUMAN (1-180): 1.01e-68: 208: 69.44		COPB2_HUMAN (1-909): 0: 562: 20.65
+	Hs
		574610 ARF4_HUMAN (1-180): 3.03e-66: 202: 72.22		COPB2_HUMAN (1-909): 0: 562: 20.65
+	Dm
		778388 ARF4_DROME (1-180): 4.46e-73: 219: 72.78		Q9W0B8_DROME (2-444): 2.94e-52: 203: 17.17
+	Dm
		897483 ARF1_DROME (1-181): 5.18e-68: 206: 78.45		Q9W0B8_DROME (2-444): 2.94e-52: 203: 17.17
+	Sc
		503103 ARF1_YEAST (1-181): 6.31e-68: 206: 100.00		COPB2_YEAST (131-923): 2.71e-52: 201: 9.21
+	Hs
		903100 RAB1A_HUMAN (5-180): 3.95e-67: 205: 20.99		WDR5_HUMAN (408-680): 1.68e-50: 184: 8.50
+	Hs
		903508 RAB1B_HUMAN (5-180): 7.15e-67: 204: 20.99		WDR5_HUMAN (408-680): 1.68e-50: 184: 8.50
+	Hs
		574641 ARF4_HUMAN (1-180): 3.03e-66: 202: 72.22		WDR5_HUMAN (408-680): 1.68e-50: 184: 8.50
+	Dm
		248478 ARF4_DROME (1-180): 4.46e-73: 219: 72.78		COPB2_DROME (242-485): 7.33e-35: 146: 10.23
+	Dm
		248479 ARF1_DROME (1-181): 5.18e-68: 206: 78.45		COPB2_DROME (242-485): 7.33e-35: 146: 10.23