HitPredict

Interactor 1: ARF1 (P11076)
ADP-ribosylation factor 1 (EC 3.6.5.2)
Gene: ARF1

Interactor 2: GGA1 (Q06336)
ADP-ribosylation factor-binding protein GGA1 (Golgi-localized, gamma ear-containing, ARF-binding protein 1)
Gene: GGA1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.793

Property	Details
Experiments	11124697, 20601958
Identification Methods	two hybrid, affinity chromatography technology, x-ray crystallography
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	Arf~GGA_N-GAT
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 181 Sc			1 557
+	Sc
		580871 ARF2_YEAST (1-181): 9.62e-69: 208: 96.13		GGA1_YEAST (1-557): 1.68e-155: 457: 100.00
+	Sc
		580855 ARF2_YEAST (1-181): 9.62e-69: 208: 96.13		GGA2_YEAST (5-557): 4.88e-132: 398: 49.40
+	Sc
		503089 ARF1_YEAST (1-181): 6.31e-68: 206: 100.00		GGA2_YEAST (5-557): 4.88e-132: 398: 49.40
+	Hs
		913174 ARF6_HUMAN (5-179): 5.38e-71: 214: 65.71		GGA2_HUMAN (9-552): 1.76e-123: 377: 18.33
+	Hs
		950574 ARF1_HUMAN (1-180): 2.46e-68: 207: 77.22		GGA2_HUMAN (9-552): 1.76e-123: 377: 18.33
+	Hs
		897415 ARF3_HUMAN (1-180): 7.11e-68: 206: 76.11		GGA2_HUMAN (9-552): 1.76e-123: 377: 18.33
+	Hs
		212615 ARF6_HUMAN (5-179): 5.38e-71: 214: 65.71		AP1G1_HUMAN (42-553): 6.18e-115: 361: 15.02
+	Hs
		212618 ARF1_HUMAN (1-180): 2.46e-68: 207: 77.22		AP1G1_HUMAN (42-553): 6.18e-115: 361: 15.02
+	Hs
		913175 ARF6_HUMAN (5-179): 5.38e-71: 214: 65.71		GGA1_HUMAN (10-552): 1.56e-112: 350: 18.07
+	Hs
		950740 ARF5_HUMAN (1-180): 1.01e-68: 208: 69.44		GGA1_HUMAN (10-552): 1.56e-112: 350: 18.07
+	Hs
		950575 ARF1_HUMAN (1-180): 2.46e-68: 207: 77.22		GGA1_HUMAN (10-552): 1.56e-112: 350: 18.07
+	Hs
		897416 ARF3_HUMAN (1-180): 7.11e-68: 206: 76.11		GGA1_HUMAN (10-552): 1.56e-112: 350: 18.07
+	Hs
		277049 ARF5_HUMAN (1-180): 1.01e-68: 208: 69.44		STAM2_HUMAN (15-461): 1.2e-74: 248: 14.98
+	Rn
		88618 ARF6_RAT (5-179): 5.38e-71: 214: 65.71		D3ZHG8_RAT (321-552): 8.66e-31: 128: 15.70
+	Hs
		913149 ARF6_HUMAN (5-179): 5.38e-71: 214: 65.71		GGA3_HUMAN (318-552): 7.92e-29: 123: 15.29
+	Rn
		88619 ARF1_RAT (1-180): 2.46e-68: 207: 77.22		D3ZHG8_RAT (321-552): 8.66e-31: 128: 15.70
+	Rn
		88617 ARF3_RAT (1-180): 7.11e-68: 206: 76.11		D3ZHG8_RAT (321-552): 8.66e-31: 128: 15.70
+	Mm
		950589 ARF1_MOUSE (1-180): 2.46e-68: 207: 77.22		GGA3_MOUSE (317-552): 3.29e-30: 127: 15.77
+	Hs
		950568 ARF1_HUMAN (1-180): 2.46e-68: 207: 77.22		GGA3_HUMAN (318-552): 7.92e-29: 123: 15.29
+	Hs
		897409 ARF3_HUMAN (1-180): 7.11e-68: 206: 76.11		GGA3_HUMAN (318-552): 7.92e-29: 123: 15.29