HitPredict

Interactor 1: PPAL (P11117)
Lysosomal acid phosphatase (LAP) (EC 3.1.3.2)
Gene: ACP2

Interactor 2: S1PR1 (P21453)
Sphingosine 1-phosphate receptor 1 (S1P receptor 1) (S1P1) (Endothelial differentiation G-protein coupled receptor 1) (Sphingosine 1-phosphate receptor Edg-1) (S1P receptor Edg-1) (CD antigen CD363)
Gene: S1PR1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.50	0.574

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 423 Hs			1 382
+	Hs
		503235 PPAL_HUMAN (1-423): 1.42e-176: 501: 100.00		LPAR1_HUMAN (23-342): 6.22e-89: 274: 38.51
+	Hs
		328304 PPAL_HUMAN (1-423): 1.42e-176: 501: 100.00		S1PR4_HUMAN (1-329): 2.24e-81: 255: 39.76
+	Hs
		503246 PPAL_HUMAN (1-423): 1.42e-176: 501: 100.00		LPAR2_HUMAN (23-365): 5.55e-76: 240: 34.88
+	Hs
		304712 PPAL_HUMAN (1-423): 1.42e-176: 501: 100.00		S1PR2_HUMAN (13-341): 3.15e-71: 228: 49.24
+	Hs
		546819 PPAP_HUMAN (27-383): 3.16e-141: 410: 50.28		CCR1_HUMAN (27-360): 7.95e-64: 209: 14.29