HitPredict

Interactor 1: MTAP2 (P11137)
Microtubule-associated protein 2 (MAP-2)
Gene: MAP2

Interactor 2: ACTN1 (P12814)
Alpha-actinin-1 (Alpha-actinin cytoskeletal isoform) (F-actin cross-linking protein) (Non-muscle alpha-actinin-1)
Gene: ACTN1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	2777757
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 1827 Hs			1 892
+	Hs
		496188 TAU_HUMAN (1069-1827): 1.92e-50: 195: 24.72		ACTN1_HUMAN (1-892): 0: 697: 100.00
+	Hs
		211474 TAU_HUMAN (1069-1827): 1.92e-50: 195: 24.72		ACTN4_HUMAN (11-892): 0: 642: 86.74
+	Hs
		521586 TITIN_HUMAN (435-1663): 6.86e-20: 100: 9.36		ACTN1_HUMAN (1-892): 0: 697: 100.00
+	Hs
		521599 CIC_HUMAN (26-1666): 2.83e-15: 84.3: 9.15		ACTN1_HUMAN (1-892): 0: 697: 100.00
+	Hs
		211525 KI67_HUMAN (62-1729): 1.72e-23: 111: 10.84		ACTN4_HUMAN (11-892): 0: 642: 86.74
+	Hs
		211629 TITIN_HUMAN (435-1663): 6.86e-20: 100: 9.36		ACTN4_HUMAN (11-892): 0: 642: 86.74
+	Hs
		993278 TITIN_HUMAN (435-1663): 6.86e-20: 100: 9.36		ACTN3_HUMAN (18-892): 0: 642: 78.51
+	Hs
		725681 TITIN_HUMAN (435-1663): 6.86e-20: 100: 9.36		ACTN2_HUMAN (10-892): 0: 640: 80.29
+	Dm
		574825 TITIN_DROME (115-1550): 2.42e-11: 71.7: 12.58		ACTN_DROME (2-892): 0: 641: 67.39
+	Rn
		582039 TAU_RAT (1091-1827): 2.81e-57: 215: 25.10		SPTN2_RAT (225-763): 1.41e-14: 80.8: 13.69
+	Rn
		94264 F1LST4_RAT (1091-1826): 8.45e-57: 214: 25.00		SPTN2_RAT (225-763): 1.41e-14: 80.8: 13.69
+	Hs
		164558 TAU_HUMAN (1069-1827): 1.92e-50: 195: 24.72		SPTN2_HUMAN (225-763): 1.02e-15: 84.3: 14.42
+	Hs
		496865 TAU_HUMAN (1069-1827): 1.92e-50: 195: 24.72		SPTB2_HUMAN (196-761): 3.97e-14: 79.3: 12.17
+	Hs
		497586 TAU_HUMAN (1069-1827): 1.92e-50: 195: 24.72		SPTN4_HUMAN (173-588): 8.58e-09: 62: 10.82
+	Hs
		963451 SRRM2_HUMAN (9-1815): 1.97e-19: 98.1: 8.82		SPTB2_HUMAN (196-761): 3.97e-14: 79.3: 12.17
+	Hs
		963398 CIC_HUMAN (26-1666): 2.83e-15: 84.3: 9.15		SPTB2_HUMAN (196-761): 3.97e-14: 79.3: 12.17