HitPredict

Interactor 1: MTAP2 (P11137)
Microtubule-associated protein 2 (MAP-2)
Gene: MAP2

Interactor 2: KAP3 (P31323)
cAMP-dependent protein kinase type II-beta regulatory subunit
Gene: PRKAR2B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0043025 - neuronal cell body GO:0043198 - dendritic shaft
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1827 Hs			1 418
+	Hs
		503259 MTAP2_HUMAN (1-1827): 0: 638: 100.00		KAP2_HUMAN (3-413): 1.93e-125: 370: 64.81
+	Hs
		496404 TAU_HUMAN (1069-1827): 1.92e-50: 195: 24.72		KAP3_HUMAN (1-418): 3.91e-140: 408: 100.00
+	Bt
		679326 Q28869_BOVIN (1504-1827): 2.32e-44: 166: 97.53		KAP3_BOVIN (1-418): 1.79e-138: 404: 97.37
+	Hs
		496203 TAU_HUMAN (1069-1827): 1.92e-50: 195: 24.72		KAP2_HUMAN (3-413): 1.93e-125: 370: 64.81
+	Bt
		337286 Q28869_BOVIN (1504-1827): 2.32e-44: 166: 97.53		KAP2_BOVIN (3-416): 1.89e-128: 377: 65.06
+	Hs
		496157 TAU_HUMAN (1069-1827): 1.92e-50: 195: 24.72		KAP0_HUMAN (102-276): 8.25e-24: 103: 24.72