HitPredict

Interactor 1: MTAP2 (P11137)
Microtubule-associated protein 2 (MAP-2)
Gene: MAP2

Interactor 2: YAP1 (P46937)
Transcriptional coactivator YAP1 (Yes-associated protein 1) (Protein yorkie homolog) (Yes-associated protein YAP65 homolog)
Gene: YAP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.27	0.60	0.408

Property	Details
Experiments	37219487
Identification Methods	unspecified method
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1827 Hs			1 504
+	Hs
		503297 MTAP2_HUMAN (1-1827): 0: 638: 100.00		ITCH_HUMAN (3-504): 3.59e-121: 378: 15.17
+	Hs
		503299 MTAP2_HUMAN (1-1827): 0: 638: 100.00		NED4L_HUMAN (4-504): 4.82e-115: 364: 19.73
+	Hs
		503272 MTAP2_HUMAN (1-1827): 0: 638: 100.00		NEDD4_HUMAN (40-504): 2.15e-103: 338: 19.26
+	Hs
		503303 MTAP2_HUMAN (1-1827): 0: 638: 100.00		HECW2_HUMAN (13-303): 1.56e-14: 79: 14.79
+	Hs
		125172 MAP4_HUMAN (702-1795): 5.54e-67: 251: 14.08		WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54
+	Hs
		653932 MAP4_HUMAN (702-1795): 5.54e-67: 251: 14.08		YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00
+	Hs
		808609 MDC1_HUMAN (186-1801): 7.14e-66: 250: 10.01		YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00
+	Hs
		497461 TAU_HUMAN (1069-1827): 1.92e-50: 195: 24.72		NED4L_HUMAN (4-504): 4.82e-115: 364: 19.73
+	Hs
		1294841 MINT_HUMAN (44-1800): 3.69e-36: 153: 7.99		ITCH_HUMAN (3-504): 3.59e-121: 378: 15.17
+	Hs
		808869 MINT_HUMAN (44-1800): 3.69e-36: 153: 7.99		YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00
+	Hs
		125795 SRRM2_HUMAN (9-1815): 1.97e-19: 98.1: 8.82		WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54
+	Hs
		801397 KI67_HUMAN (62-1729): 1.72e-23: 111: 10.84		SMUF1_HUMAN (89-504): 7.79e-117: 363: 20.05
+	Hs
		809031 SRRM2_HUMAN (9-1815): 1.97e-19: 98.1: 8.82		YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00
+	Hs
		808716 SRCAP_HUMAN (9-1700): 1.03e-17: 92.4: 8.10		YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00
+	Dm
		54898 A1ZA72_DROME (85-1189): 1.82e-17: 91.8: 15.87		SUDX_DROME (16-504): 4.46e-109: 347: 15.74
+	Hs
		1264807 TITIN_HUMAN (435-1663): 6.86e-20: 100: 9.36		SMUF2_HUMAN (99-504): 4.95e-107: 337: 19.19
+	Hs
		497466 TAU_HUMAN (1069-1827): 1.92e-50: 195: 24.72		MAGI1_HUMAN (69-305): 1.87e-39: 155: 18.32
+	Hs
		1170084 SRCAP_HUMAN (9-1700): 1.03e-17: 92.4: 8.10		WWTR1_HUMAN (51-504): 2.59e-59: 202: 39.83
+	Dm
		54872 A1ZA72_DROME (85-1189): 1.82e-17: 91.8: 15.87		YAP1_DROME (52-268): 1.16e-44: 163: 29.25
+	Hs
		1170093 SRCAP_HUMAN (9-1700): 1.03e-17: 92.4: 8.10		HECW2_HUMAN (13-303): 1.56e-14: 79: 14.79