HitPredict

Interactor 1: MTAP2 (P11137)
Microtubule-associated protein 2 (MAP-2)
Gene: MAP2

Interactor 2: GRB2 (P62993)
Growth factor receptor-bound protein 2 (Adapter protein GRB2) (Protein Ash) (SH2/SH3 adapter GRB2)
Gene: GRB2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.78	0.60	0.686

Property	Details
Experiments	10781592, 11546790, 15536091
Identification Methods	pull down, filter binding, coimmunoprecipitation, enzyme linked immunosorbent assay, far western blotting
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1827 Hs			1 217
+	Hs
		411964 MTAP2_HUMAN (1-1827): 0: 638: 100.00		FYN_HUMAN (161-215): 4.44e-14: 72.3: 31.58
+	Hs
		503258 MTAP2_HUMAN (1-1827): 0: 638: 100.00		SRC_HUMAN (161-215): 3.76e-11: 63.8: 31.58
+	Hs
		496788 TAU_HUMAN (1069-1827): 1.92e-50: 195: 24.72		GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00
+	Hs
		924473 MAP1A_HUMAN (112-1821): 1.34e-37: 157: 9.61		GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00
+	Hs
		924808 MINT_HUMAN (44-1800): 3.69e-36: 153: 7.99		GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00
+	Hs
		924760 PRG4_HUMAN (1034-1790): 4.95e-28: 126: 9.94		GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00
+	Hs
		557613 MAP4_HUMAN (702-1795): 5.54e-67: 251: 14.08		NCK1_HUMAN (5-145): 9.45e-23: 96.3: 33.14
+	Hs
		411566 TAU_HUMAN (1069-1827): 1.92e-50: 195: 24.72		LCK_HUMAN (3-202): 3.69e-37: 137: 28.91
+	Hs
		337321 TAU_HUMAN (1069-1827): 1.92e-50: 195: 24.72		ABL1_HUMAN (4-139): 4.39e-22: 95.5: 35.46
+	Hs
		411960 TAU_HUMAN (1069-1827): 1.92e-50: 195: 24.72		FYN_HUMAN (161-215): 4.44e-14: 72.3: 31.58
+	Hs
		496189 TAU_HUMAN (1069-1827): 1.92e-50: 195: 24.72		SRC_HUMAN (161-215): 3.76e-11: 63.8: 31.58
+	Hs
		557777 MINT_HUMAN (44-1800): 3.69e-36: 153: 7.99		NCK1_HUMAN (5-145): 9.45e-23: 96.3: 33.14
+	Hs
		337387 KI67_HUMAN (62-1729): 1.72e-23: 111: 10.84		ABL1_HUMAN (4-139): 4.39e-22: 95.5: 35.46
+	Hs
		412078 KI67_HUMAN (62-1729): 1.72e-23: 111: 10.84		FYN_HUMAN (161-215): 4.44e-14: 72.3: 31.58
+	Hs
		64077 L37A2_HUMAN (998-1689): 2.46e-24: 114: 9.44		SRC_HUMAN (161-215): 3.76e-11: 63.8: 31.58
+	Hs
		522847 KI67_HUMAN (62-1729): 1.72e-23: 111: 10.84		SRC_HUMAN (161-215): 3.76e-11: 63.8: 31.58
+	Hs
		789101 KI67_HUMAN (62-1729): 1.72e-23: 111: 10.84		FRK_HUMAN (150-212): 6.98e-11: 62.7: 27.78
+	Hs
		855816 TITIN_HUMAN (435-1663): 6.86e-20: 100: 9.36		VAV2_HUMAN (3-56): 4.83e-11: 63.5: 38.18
+	Hs
		434084 SRRM2_HUMAN (9-1815): 1.97e-19: 98.1: 8.82		LYN_HUMAN (129-215): 1.44e-11: 65: 22.47
+	Hs
		523118 CIC_HUMAN (26-1666): 2.83e-15: 84.3: 9.15		SRC_HUMAN (161-215): 3.76e-11: 63.8: 31.58