HitPredict

Interactor 1: MTAP2 (P11137)
Microtubule-associated protein 2 (MAP-2)
Gene: MAP2

Interactor 2: TBA1A (Q71U36)
Tubulin alpha-1A chain (EC 3.6.5.-) (Alpha-tubulin 3) (Tubulin B-alpha-1) (Tubulin alpha-3 chain) [Cleaved into: Detyrosinated tubulin alpha-1A chain]
Gene: TUBA1A

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.69	0.60	0.646

Property	Details
Experiments	7591286, 18341635, 2777757
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000226 - microtubule cytoskeleton organization GO:0005198 - structural molecule activity GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005874 - microtubule
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1827 Hs			1 451
+	Hs
		653957 MAP4_HUMAN (702-1795): 5.54e-67: 251: 14.08		TBA1B_HUMAN (1-440): 0: 715: 99.55
+	Mm
		649204 MAP4_MOUSE (879-1810): 3.89e-61: 232: 18.09		TBA1A_MOUSE (1-440): 0: 713: 100.00
+	Rn
		582020 TAU_RAT (1091-1827): 2.81e-57: 215: 25.10		TBA1B_RAT (1-440): 0: 715: 99.55
+	Hs
		92367 E9PBC6_HUMAN (24-1772): 6.99e-56: 217: 10.15		TBA1A_HUMAN (1-440): 0: 713: 100.00
+	Rn
		94246 F1LST4_RAT (1091-1826): 8.45e-57: 214: 25.00		TBA1B_RAT (1-440): 0: 715: 99.55
+	Hs
		497515 TAU_HUMAN (1069-1827): 1.92e-50: 195: 24.72		TBA1C_HUMAN (1-451): 0: 726: 98.00
+	Mm
		399082 TAU_MOUSE (1114-1827): 2.74e-51: 197: 25.53		TBA1B_MOUSE (1-440): 0: 715: 99.55
+	Hs
		496818 TAU_HUMAN (1069-1827): 1.92e-50: 195: 24.72		TBA4A_HUMAN (1-450): 0: 717: 96.00
+	Hs
		496817 TAU_HUMAN (1069-1827): 1.92e-50: 195: 24.72		TBA1B_HUMAN (1-440): 0: 715: 99.55
+	Mm
		498002 TAU_MOUSE (1114-1827): 2.74e-51: 197: 25.53		TBA1A_MOUSE (1-440): 0: 713: 100.00
+	Hs
		497220 TAU_HUMAN (1069-1827): 1.92e-50: 195: 24.72		TBA1A_HUMAN (1-440): 0: 713: 100.00
+	Hs
		497683 TAU_HUMAN (1069-1827): 1.92e-50: 195: 24.72		TBA8_HUMAN (1-440): 0: 701: 90.68
+	Mm
		498012 TAU_MOUSE (1114-1827): 2.74e-51: 197: 25.53		TBB5_MOUSE (1-439): 0: 695: 40.77
+	Hs
		427983 TAU_HUMAN (1069-1827): 1.92e-50: 195: 24.72		TBB5_HUMAN (1-439): 0: 695: 40.77
+	Hs
		496819 TAU_HUMAN (1069-1827): 1.92e-50: 195: 24.72		TBB4B_HUMAN (1-437): 0: 693: 40.50
+	Dm
		415626 FUTSC_DROME (98-1807): 1.18e-31: 138: 9.24		TBA1_DROME (1-439): 0: 711: 97.95
+	Dm
		415643 FUTSC_DROME (98-1807): 1.18e-31: 138: 9.24		TBA2_DROME (1-451): 0: 709: 94.68
+	Dm
		415665 FUTSC_DROME (98-1807): 1.18e-31: 138: 9.24		TBA3_DROME (1-439): 0: 708: 97.49
+	Rn
		713902 MAP1A_RAT (8-1820): 3.31e-29: 130: 9.82		TBA1A_RAT (1-440): 0: 713: 100.00
+	Hs
		92120 NACAM_HUMAN (789-1797): 1.66e-25: 118: 10.21		TBA1A_HUMAN (1-440): 0: 713: 100.00