HitPredict

Interactor 1: HSP7C (P11142)
Heat shock cognate 71 kDa protein (EC 3.6.4.10) (Heat shock 70 kDa protein 8) (Heat shock protein family A member 8) (Lipopolysaccharide-associated protein 1) (LAP-1) (LPS-associated protein 1)
Gene: HSPA8

Interactor 2: STIP1 (P31948)
Stress-induced-phosphoprotein 1 (STI1) (Hsc70/Hsp90-organizing protein) (Hop) (Renal carcinoma antigen NY-REN-11) (Transformation-sensitive protein IEF SSP 3521)
Gene: STIP1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.88	0.60	0.729

Property	Details
Experiments	35271311, 33239621, 9774640, 25864199, 10567422, 11093761
Identification Methods	affinity chromatography technology, pull down, far western blotting
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005829 - cytosol GO:0101031 - protein folding chaperone complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 646 Hs			1 543
+	Hs
		684439 HS71L_HUMAN (2-646): 0: 966: 82.48		STIP1_HUMAN (1-543): 2.75e-98: 309: 100.00
+	Hs
		564017 HSP76_HUMAN (6-646): 0: 955: 77.54		STIP1_HUMAN (1-543): 2.75e-98: 309: 100.00
+	At
		1338008 HS704_ARATH (3-646): 0: 948: 76.35		HSOP1_ARATH (3-543): 3.3e-98: 310: 41.96
+	Hs
		483776 HS71B_HUMAN (1-646): 0: 948: 84.37		STIP1_HUMAN (1-543): 2.75e-98: 309: 100.00
+	Hs
		684557 HSP72_HUMAN (2-646): 0: 940: 85.47		STIP1_HUMAN (1-543): 2.75e-98: 309: 100.00
+	Hs
		564151 HSP76_HUMAN (6-646): 0: 955: 77.54		SGTB_HUMAN (213-348): 5.73e-32: 126: 31.39
+	Hs
		1120567 Q53FA3_HUMAN (2-646): 0: 967: 82.33		DNJC7_HUMAN (209-487): 3.28e-26: 113: 18.28
+	Hs
		504631 HSP7C_HUMAN (1-646): 0: 967: 100.00		DNJC7_HUMAN (209-487): 3.28e-26: 113: 18.28
+	Hs
		714055 HS71L_HUMAN (2-646): 0: 966: 82.48		DNJC7_HUMAN (209-487): 3.28e-26: 113: 18.28
+	Hs
		564163 HSP76_HUMAN (6-646): 0: 955: 77.54		DNJC7_HUMAN (209-487): 3.28e-26: 113: 18.28
+	Hs
		483768 HS71A_HUMAN (1-646): 0: 948: 84.37		DNJC7_HUMAN (209-487): 3.28e-26: 113: 18.28
+	Hs
		483801 HS71B_HUMAN (1-646): 0: 948: 84.37		DNJC7_HUMAN (209-487): 3.28e-26: 113: 18.28
+	Hs
		174578 HSP7C_HUMAN (1-646): 0: 967: 100.00		OGT1_HUMAN (5-261): 5.16e-18: 90: 13.57
+	Hs
		871751 HSP72_HUMAN (2-646): 0: 940: 85.47		DNJC7_HUMAN (209-487): 3.28e-26: 113: 18.28
+	Hs
		564188 HSP76_HUMAN (6-646): 0: 955: 77.54		RPAP3_HUMAN (2-141): 4.46e-20: 96.1: 27.14
+	Hs
		297027 HSP7C_HUMAN (1-646): 0: 967: 100.00		TOM70_HUMAN (207-543): 4.08e-13: 73.8: 11.00
+	Dm
		505095 HSP7D_DROME (1-612): 0: 938: 86.60		Q9VJD4_DROME (215-353): 5.45e-21: 96: 24.46
+	Mm
		926144 HSP7C_MOUSE (1-646): 0: 967: 99.85		SGTA_MOUSE (202-327): 4.16e-10: 63.2: 33.33
+	Hs
		213468 HSP7C_HUMAN (1-646): 0: 967: 100.00		SGTA_HUMAN (202-327): 3.98e-09: 60.1: 32.54
+	Hs
		871541 HSP72_HUMAN (2-646): 0: 940: 85.47		SPAG1_HUMAN (405-527): 2.93e-11: 68.4: 14.63