Interactor 1: HSP7C (P11142)
Heat shock cognate 71 kDa protein (EC 3.6.4.10) (Heat shock 70 kDa protein 8) (Heat shock protein family A member 8) (Lipopolysaccharide-associated protein 1) (LAP-1) (LPS-associated protein 1)
Gene: HSPA8

Interactor 2: HSP74 (P34932)
Heat shock 70 kDa protein 4 (HSP70RY) (Heat shock 70-related protein APG-2) (Heat shock protein family H member 2)
Gene: HSPA4

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.976

The method score is based on:

Property Details
Experiments 35271311, 34349018, 27684187, 29568061, 25864199, 30021884, 33961781, 32687490, 37071682, 25036637, unassigned1655, 22990239
Identification Methods affinity chromatography technology, cross-linking study, proximity labelling technology, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains HSP70~HSP70
Common GO terms GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0006457 - protein folding
GO:0006986 - response to unfolded protein
and 2 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 646
Hs

1 840
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024