HitPredict

Interactor 1: HSP7C (P11142)
Heat shock cognate 71 kDa protein (EC 3.6.4.10) (Heat shock 70 kDa protein 8) (Heat shock protein family A member 8) (Lipopolysaccharide-associated protein 1) (LAP-1) (LPS-associated protein 1)
Gene: HSPA8

Interactor 2: CDN2A (P42771)
Cyclin-dependent kinase inhibitor 2A (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (Multiple tumor suppressor 1) (MTS-1) (p16-INK4a) (p16-INK4) (p16INK4A)
Gene: CDKN2A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.516

Property	Details
Experiments	17955473
Identification Methods	pull down
Interaction Type	direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0045892 - negative regulation of DNA-templated transcription and 1 others more... GO:0051726 - regulation of cell cycle
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 646 Hs			1 156
+	Hs
		503916 HSP7C_HUMAN (1-646): 0: 967: 100.00		ANK2_HUMAN (3-155): 1.76e-37: 137: 17.37
+	Hs
		483759 HS71A_HUMAN (1-646): 0: 948: 84.37		ANK2_HUMAN (3-155): 1.76e-37: 137: 17.37
+	Hs
		503777 HSP7C_HUMAN (1-646): 0: 967: 100.00		RIPK4_HUMAN (9-155): 1.21e-30: 117: 25.68
+	Hs
		504758 HSP7C_HUMAN (1-646): 0: 967: 100.00		Q9H4D1_HUMAN (9-155): 2.04e-30: 116: 25.68
+	Hs
		564048 HSP76_HUMAN (6-646): 0: 955: 77.54		RIPK4_HUMAN (9-155): 1.21e-30: 117: 25.68
+	Hs
		564185 HSP76_HUMAN (6-646): 0: 955: 77.54		Q9H4D1_HUMAN (9-155): 2.04e-30: 116: 25.68
+	Hs
		504362 HSP7C_HUMAN (1-646): 0: 967: 100.00		ANKH1_HUMAN (68-155): 3.32e-18: 82.3: 19.32
+	Hs
		504719 HSP7C_HUMAN (1-646): 0: 967: 100.00		TANC1_HUMAN (56-154): 1.3e-14: 71.9: 21.00
+	Hs
		504882 HSP7C_HUMAN (1-646): 0: 967: 100.00		RAI14_HUMAN (1-64): 1.97e-11: 62.7: 21.21
+	Hs
		276135 HS71A_HUMAN (1-646): 0: 948: 84.37		PSD10_HUMAN (1-85): 4.57e-12: 63.1: 23.86