Interactor 1: HSP7C (P11142)
Heat shock cognate 71 kDa protein (EC 3.6.4.10) (Heat shock 70 kDa protein 8) (Heat shock protein family A member 8) (Lipopolysaccharide-associated protein 1) (LAP-1) (LPS-associated protein 1)
Gene: HSPA8

Interactor 2: HSP72 (P54652)
Heat shock-related 70 kDa protein 2 (Heat shock 70 kDa protein 2) (Heat shock protein family A member 2)
Gene: HSPA2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.92 1.00 0.960

The method score is based on:

Property Details
Experiments 33961781, 34349018, 35235311, 28514442, 29568061, 25036637, unassigned1655
Identification Methods affinity chromatography technology, cross-linking study, proximity labelling technology, anti tag coimmunoprecipitation, pull down
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains HSP70~HSP70
Common GO terms GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane
and 14 others

more...

Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 646
Hs

1 639
+ Hs
+ Hs
+ Mm
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+ Mm
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Last updated: 15 Jul 2024