HitPredict

Interactor 1: HSP7C (P11142)
Heat shock cognate 71 kDa protein (EC 3.6.4.10) (Heat shock 70 kDa protein 8) (Heat shock protein family A member 8) (Lipopolysaccharide-associated protein 1) (LAP-1) (LPS-associated protein 1)
Gene: HSPA8

Interactor 2: RIPK4 (P57078)
Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain-containing protein 3) (PKC-delta-interacting protein kinase)
Gene: RIPK4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	26972000
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005737 - cytoplasm GO:0016020 - membrane
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 646 Hs			1 832
+	Hs
		564048 HSP76_HUMAN (6-646): 0: 955: 77.54		RIPK4_HUMAN (1-832): 0: 726: 100.00
+	Hs
		504758 HSP7C_HUMAN (1-646): 0: 967: 100.00		Q9H4D1_HUMAN (1-832): 0: 697: 90.75
+	Hs
		564185 HSP76_HUMAN (6-646): 0: 955: 77.54		Q9H4D1_HUMAN (1-832): 0: 697: 90.75
+	Hs
		503916 HSP7C_HUMAN (1-646): 0: 967: 100.00		ANK2_HUMAN (592-832): 1.31e-65: 241: 27.89
+	Hs
		483759 HS71A_HUMAN (1-646): 0: 948: 84.37		ANK2_HUMAN (592-832): 1.31e-65: 241: 27.89
+	Hs
		201749 HSP7C_HUMAN (1-646): 0: 967: 100.00		RIPK2_HUMAN (31-276): 6.59e-54: 197: 44.94
+	Hs
		201765 HS71L_HUMAN (2-646): 0: 966: 82.48		RIPK2_HUMAN (31-276): 6.59e-54: 197: 44.94
+	Hs
		201751 HSP76_HUMAN (6-646): 0: 955: 77.54		RIPK2_HUMAN (31-276): 6.59e-54: 197: 44.94
+	Hs
		714021 HS71L_HUMAN (2-646): 0: 966: 82.48		ANKK1_HUMAN (342-643): 1.15e-46: 180: 19.47
+	Hs
		201771 HSP72_HUMAN (2-646): 0: 940: 85.47		RIPK2_HUMAN (31-276): 6.59e-54: 197: 44.94
+	Hs
		505013 HSP7C_HUMAN (1-646): 0: 967: 100.00		RIPK3_HUMAN (21-371): 4.07e-34: 139: 30.39
+	Hs
		714103 HS71L_HUMAN (2-646): 0: 966: 82.48		RIPK3_HUMAN (21-371): 4.07e-34: 139: 30.39
+	Hs
		504035 HSP7C_HUMAN (1-646): 0: 967: 100.00		RIPK1_HUMAN (19-278): 1.18e-32: 137: 34.31
+	Hs
		713961 HS71L_HUMAN (2-646): 0: 966: 82.48		RIPK1_HUMAN (19-278): 1.18e-32: 137: 34.31
+	Hs
		504362 HSP7C_HUMAN (1-646): 0: 967: 100.00		ANKH1_HUMAN (384-541): 3.69e-19: 95.3: 14.47