HitPredict

Interactor 1: HSP7C (P11142)
Heat shock cognate 71 kDa protein (EC 3.6.4.10) (Heat shock 70 kDa protein 8) (Heat shock protein family A member 8) (Lipopolysaccharide-associated protein 1) (LAP-1) (LPS-associated protein 1)
Gene: HSPA8

Interactor 2: 1433G (P61981)
14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed]
Gene: YWHAG

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	32687490
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005925 - focal adhesion GO:0016020 - membrane and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 646 Hs			1 247
+	Hs
		503828 HSP7C_HUMAN (1-646): 0: 967: 100.00		1433E_HUMAN (1-244): 2.02e-141: 398: 63.53
+	Mm
		910222 HSP7C_MOUSE (1-646): 0: 967: 99.85		1433E_MOUSE (1-244): 2.02e-141: 398: 63.53
+	Sp
		788712 HSP71_SCHPO (5-646): 0: 978: 75.23		RAD24_SCHPO (3-247): 8.91e-135: 381: 60.82
+	Hs
		503945 HSP7C_HUMAN (1-646): 0: 967: 100.00		1433F_HUMAN (1-246): 2.5e-135: 382: 86.99
+	At
		788425 HS704_ARATH (3-646): 0: 948: 76.35		14331_ARATH (4-244): 4.02e-141: 397: 59.67
+	At
		612300 HS701_ARATH (3-646): 0: 944: 76.35		14333_ARATH (1-244): 4.4e-142: 400: 61.79
+	At
		612299 HS701_ARATH (3-646): 0: 944: 76.35		14331_ARATH (4-244): 4.02e-141: 397: 59.67
+	At
		250053 HSP7C_ARATH (3-646): 0: 931: 74.81		14331_ARATH (4-244): 4.02e-141: 397: 59.67
+	At
		612330 HS702_ARATH (3-646): 0: 929: 75.77		14332_ARATH (4-244): 1.39e-141: 398: 61.32
+	Hs
		503532 HSP7C_HUMAN (1-646): 0: 967: 100.00		1433B_HUMAN (2-247): 1.91e-109: 317: 75.40
+	Hs
		503857 HSP7C_HUMAN (1-646): 0: 967: 100.00		1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59
+	Hs
		713939 HS71L_HUMAN (2-646): 0: 966: 82.48		1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59
+	Hs
		503478 HSP7C_HUMAN (1-646): 0: 967: 100.00		1433T_HUMAN (2-245): 5.53e-105: 305: 70.33
+	Hs
		503533 HSP7C_HUMAN (1-646): 0: 967: 100.00		1433S_HUMAN (2-245): 1.86e-98: 289: 65.16
+	Mm
		565423 HSP72_MOUSE (2-612): 0: 936: 87.77		1433Z_MOUSE (2-245): 8.46e-109: 315: 74.59