HitPredict

Interactor 1: HSP7C (P11142)
Heat shock cognate 71 kDa protein (EC 3.6.4.10) (Heat shock 70 kDa protein 8) (Heat shock protein family A member 8) (Lipopolysaccharide-associated protein 1) (LAP-1) (LPS-associated protein 1)
Gene: HSPA8

Interactor 2: GBB1 (P62873)
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 (Transducin beta chain 1)
Gene: GNB1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	33961781, 32687490
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005765 - lysosomal membrane GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0016020 - membrane and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 646 Hs			1 340
+	Hs
		503848 HSP7C_HUMAN (1-646): 0: 967: 100.00		GBB2_HUMAN (1-340): 1e-105: 314: 90.29
+	Hs
		564054 HSP76_HUMAN (6-646): 0: 955: 77.54		GBB2_HUMAN (1-340): 1e-105: 314: 90.29
+	Hs
		920985 Q53FC7_HUMAN (6-646): 0: 951: 77.07		GBB1_HUMAN (1-340): 7.02e-105: 312: 100.00
+	Hs
		483785 HS71B_HUMAN (1-646): 0: 948: 84.37		GBB2_HUMAN (1-340): 1e-105: 314: 90.29
+	Hs
		871525 HSP72_HUMAN (2-646): 0: 940: 85.47		GBB2_HUMAN (1-340): 1e-105: 314: 90.29
+	Hs
		871524 HSP72_HUMAN (2-646): 0: 940: 85.47		GBB1_HUMAN (1-340): 7.02e-105: 312: 100.00
+	Hs
		504344 HSP7C_HUMAN (1-646): 0: 967: 100.00		WDR5B_HUMAN (71-340): 2.74e-83: 257: 25.18
+	Hs
		503817 HSP7C_HUMAN (1-646): 0: 967: 100.00		WDR5_HUMAN (4-211): 4.16e-56: 187: 20.93
+	Hs
		504412 HSP7C_HUMAN (1-646): 0: 967: 100.00		POC1A_HUMAN (10-125): 4.11e-27: 112: 17.24
+	Hs
		714020 HS71L_HUMAN (2-646): 0: 966: 82.48		POC1A_HUMAN (10-125): 4.11e-27: 112: 17.24
+	Hs
		564125 HSP76_HUMAN (6-646): 0: 955: 77.54		POC1A_HUMAN (10-125): 4.11e-27: 112: 17.24
+	Hs
		503614 HSP7C_HUMAN (1-646): 0: 967: 100.00		LIS1_HUMAN (259-340): 1.35e-18: 87.8: 23.17