HitPredict

Interactor 1: HSP7C (P11142)
Heat shock cognate 71 kDa protein (EC 3.6.4.10) (Heat shock 70 kDa protein 8) (Heat shock protein family A member 8) (Lipopolysaccharide-associated protein 1) (LAP-1) (LPS-associated protein 1)
Gene: HSPA8

Interactor 2: FOXC1 (Q12948)
Forkhead box protein C1 (Forkhead-related protein FKHL7) (Forkhead-related transcription factor 3) (FREAC-3)
Gene: FOXC1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001822 - kidney development GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0021549 - cerebellum development
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 646 Hs			1 553
+	Hs
		871547 HSP72_HUMAN (2-646): 0: 940: 85.47		FOXC1_HUMAN (1-553): 8.84e-82: 267: 100.00
+	Hs
		503896 HSP7C_HUMAN (1-646): 0: 967: 100.00		FOXK1_HUMAN (73-399): 1.02e-47: 179: 25.93
+	Hs
		503980 HSP7C_HUMAN (1-646): 0: 967: 100.00		FOXO1_HUMAN (50-463): 3.5e-45: 171: 18.76
+	Hs
		208903 HSP72_HUMAN (2-646): 0: 940: 85.47		FOXS1_HUMAN (64-294): 2.27e-57: 196: 42.15
+	Hs
		503991 HSP7C_HUMAN (1-646): 0: 967: 100.00		FOXD4_HUMAN (18-412): 2.13e-34: 137: 26.77