HitPredict

Interactor 1: HSP7C (P11142)
Heat shock cognate 71 kDa protein (EC 3.6.4.10) (Heat shock 70 kDa protein 8) (Heat shock protein family A member 8) (Lipopolysaccharide-associated protein 1) (LAP-1) (LPS-associated protein 1)
Gene: HSPA8

Interactor 2: ILK (Q13418)
Integrin-linked protein kinase (EC 2.7.11.1) (59 kDa serine/threonine-protein kinase) (Beta-integrin-linked kinase) (ILK-1) (ILK-2) (p59ILK)
Gene: ILK

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	28514442, 33961781, 32687490
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0005925 - focal adhesion GO:0016020 - membrane
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 646 Hs			1 452
+	Hs
		713958 HS71L_HUMAN (2-646): 0: 966: 82.48		ILK_HUMAN (1-452): 1.6e-146: 427: 100.00
+	Mm
		223283 HSP7C_MOUSE (1-646): 0: 967: 99.85		ILK_MOUSE (1-452): 6.16e-146: 425: 99.56
+	Hs
		564070 HSP76_HUMAN (6-646): 0: 955: 77.54		ILK_HUMAN (1-452): 1.6e-146: 427: 100.00
+	Hs
		871556 HSP72_HUMAN (2-646): 0: 940: 85.47		ILK_HUMAN (1-452): 1.6e-146: 427: 100.00
+	Hs
		411570 HSP7C_HUMAN (1-646): 0: 967: 100.00		LCK_HUMAN (167-449): 1.86e-109: 334: 21.99
+	Hs
		411586 HSP76_HUMAN (6-646): 0: 955: 77.54		LCK_HUMAN (167-449): 1.86e-109: 334: 21.99
+	Hs
		503340 HSP7C_HUMAN (1-646): 0: 967: 100.00		SRC_HUMAN (173-448): 1.71e-98: 307: 24.56
+	Hs
		433227 HSP7C_HUMAN (1-646): 0: 967: 100.00		YES_HUMAN (176-448): 5.77e-98: 305: 26.60