HitPredict

Interactor 1: HSP7C (P11142)
Heat shock cognate 71 kDa protein (EC 3.6.4.10) (Heat shock 70 kDa protein 8) (Heat shock protein family A member 8) (Lipopolysaccharide-associated protein 1) (LAP-1) (LPS-associated protein 1)
Gene: HSPA8

Interactor 2: LRRK1 (Q38SD2)
Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1)
Gene: LRRK1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	24510904, 24947832
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 646 Hs			1 2015
+	At
		612329 HS701_ARATH (3-646): 0: 944: 76.35		BRL2_ARATH (4-345): 2.29e-33: 143: 13.07
+	Hs
		1130801 V9HW22_HUMAN (1-646): 0: 967: 100.00		LRRK2_HUMAN (47-285): 1.02e-20: 102: 11.65
+	Hs
		504206 HSP7C_HUMAN (1-646): 0: 967: 100.00		LRRK2_HUMAN (47-285): 1.02e-20: 102: 11.65
+	Hs
		2872 A0A0G2JIW1_HUMAN (1-646): 0: 948: 84.37		LRRK2_HUMAN (47-285): 1.02e-20: 102: 11.65
+	Hs
		483766 HS71A_HUMAN (1-646): 0: 948: 84.37		LRRK2_HUMAN (47-285): 1.02e-20: 102: 11.65
+	Hs
		504776 HSP7C_HUMAN (1-646): 0: 967: 100.00		LRC40_HUMAN (280-489): 5.62e-14: 79.3: 32.19
+	Hs
		871790 HSP72_HUMAN (2-646): 0: 940: 85.47		LRC40_HUMAN (280-489): 5.62e-14: 79.3: 32.19