HitPredict

Interactor 1: HSP7C (P11142)
Heat shock cognate 71 kDa protein (EC 3.6.4.10) (Heat shock 70 kDa protein 8) (Heat shock protein family A member 8) (Lipopolysaccharide-associated protein 1) (LAP-1) (LPS-associated protein 1)
Gene: HSPA8

Interactor 2: MAVS (Q7Z434)
Mitochondrial antiviral-signaling protein (MAVS) (CARD adapter inducing interferon beta) (Cardif) (Interferon beta promoter stimulator protein 1) (IPS-1) (Putative NF-kappa-B-activating protein 031N) (Virus-induced-signaling adapter) (VISA)
Gene: MAVS

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.50	0.574

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 646 Hs			1 540
+	Hs
		871638 HSP72_HUMAN (2-646): 0: 940: 85.47		MAVS_HUMAN (1-540): 1.73e-73: 245: 100.00
+	Hs
		504318 HSP7C_HUMAN (1-646): 0: 967: 100.00		HUWE1_HUMAN (79-539): 8.05e-24: 108: 13.36
+	Hs
		503745 HSP7C_HUMAN (1-646): 0: 967: 100.00		SC24C_HUMAN (116-429): 9.64e-11: 66.7: 15.43
+	Hs
		504583 HSP7C_HUMAN (1-646): 0: 967: 100.00		CHAP1_HUMAN (196-539): 2.7e-10: 65.2: 10.38
+	Hs
		504610 HSP7C_HUMAN (1-646): 0: 967: 100.00		CIC_HUMAN (40-516): 7.01e-10: 64.1: 12.58
+	Hs
		871744 HSP72_HUMAN (2-646): 0: 940: 85.47		CIC_HUMAN (40-516): 7.01e-10: 64.1: 12.58