HitPredict

Interactor 1: HSP7C (P11142)
Heat shock cognate 71 kDa protein (EC 3.6.4.10) (Heat shock 70 kDa protein 8) (Heat shock protein family A member 8) (Lipopolysaccharide-associated protein 1) (LAP-1) (LPS-associated protein 1)
Gene: HSPA8

Interactor 2: ABI1 (Q8IZP0)
Abl interactor 1 (Abelson interactor 1) (Abi-1) (Abl-binding protein 4) (AblBP4) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (Nap1-binding protein) (Nap1BP) (Spectrin SH3 domain-binding protein 1) (e3B1)
Gene: ABI1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.633

Property	Details
Experiments	31980649, unassigned2173, 15048123
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0014069 - postsynaptic density GO:0045296 - cadherin binding GO:0070062 - extracellular exosome
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 646 Hs			1 508
+	Hs
		564120 HSP76_HUMAN (6-646): 0: 955: 77.54		ABI1_HUMAN (1-508): 3.82e-124: 374: 100.00
+	Hs
		504070 HSP7C_HUMAN (1-646): 0: 967: 100.00		SRC8_HUMAN (291-502): 1.23e-34: 138: 20.72
+	Hs
		504095 HSP7C_HUMAN (1-646): 0: 967: 100.00		LASP1_HUMAN (285-503): 9.91e-33: 127: 19.28
+	Hs
		503416 HSP7C_HUMAN (1-646): 0: 967: 100.00		NCF2_HUMAN (211-501): 2.81e-27: 117: 12.29
+	Hs
		504923 HSP7C_HUMAN (1-646): 0: 967: 100.00		DBNL_HUMAN (316-503): 2.32e-17: 86.1: 20.53
+	Hs
		505017 HSP7C_HUMAN (1-646): 0: 967: 100.00		CD2AP_HUMAN (451-508): 2.26e-14: 77.9: 40.68
+	Hs
		871823 HSP72_HUMAN (2-646): 0: 940: 85.47		DBNL_HUMAN (316-503): 2.32e-17: 86.1: 20.53