HitPredict

Interactor 1: HSP7C (P11142)
Heat shock cognate 71 kDa protein (EC 3.6.4.10) (Heat shock 70 kDa protein 8) (Heat shock protein family A member 8) (Lipopolysaccharide-associated protein 1) (LAP-1) (LPS-associated protein 1)
Gene: HSPA8

Interactor 2: CNN2 (Q99439)
Calponin-2 (Calponin H2, smooth muscle) (Neutral calponin)
Gene: CNN2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	28514442, 33961781, 32687490
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0005925 - focal adhesion GO:0016020 - membrane GO:0045296 - cadherin binding
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 646 Hs			1 309
+	Hs
		504118 HSP7C_HUMAN (1-646): 0: 967: 100.00		CNN3_HUMAN (4-306): 3.73e-147: 418: 65.48
+	Hs
		503646 HSP7C_HUMAN (1-646): 0: 967: 100.00		IQGA1_HUMAN (7-138): 1.55e-37: 144: 18.75
+	Hs
		503732 HSP7C_HUMAN (1-646): 0: 967: 100.00		VAV2_HUMAN (49-140): 1.3e-14: 76.2: 32.32