HitPredict

Interactor 1: HSP7C (P11142)
Heat shock cognate 71 kDa protein (EC 3.6.4.10) (Heat shock 70 kDa protein 8) (Heat shock protein family A member 8) (Lipopolysaccharide-associated protein 1) (LAP-1) (LPS-associated protein 1)
Gene: HSPA8

Interactor 2: MYD88 (Q99836)
Myeloid differentiation primary response protein MyD88
Gene: MYD88

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	21827211
Identification Methods	pull down
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0009986 - cell surface and 1 others more... GO:0045471 - response to ethanol
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 646 Hs			1 296
+	Mm
		607539 HSP7C_MOUSE (1-646): 0: 967: 99.85		MYD88_MOUSE (1-296): 6.79e-129: 370: 81.76
+	Hs
		714057 HS71L_HUMAN (2-646): 0: 966: 82.48		MYD88_HUMAN (14-296): 4.31e-123: 355: 100.00
+	Hs
		564165 HSP76_HUMAN (6-646): 0: 955: 77.54		MYD88_HUMAN (14-296): 4.31e-123: 355: 100.00
+	Hs
		120127 HSP7C_HUMAN (1-646): 0: 967: 100.00		TLR4_HUMAN (153-293): 2.58e-46: 168: 26.00
+	Mm
		926167 HSP7C_MOUSE (1-646): 0: 967: 99.85		TLR4_MOUSE (147-293): 1.82e-45: 166: 24.36
+	Hs
		237463 HSP7C_HUMAN (1-646): 0: 967: 100.00		TLR2_HUMAN (161-293): 5.15e-45: 164: 23.78