HitPredict

Interactor 1: HSP7C (P11142)
Heat shock cognate 71 kDa protein (EC 3.6.4.10) (Heat shock 70 kDa protein 8) (Heat shock protein family A member 8) (Lipopolysaccharide-associated protein 1) (LAP-1) (LPS-associated protein 1)
Gene: HSPA8

Interactor 2: AP1M1 (Q9BXS5)
AP-1 complex subunit mu-1 (AP-mu chain family member mu1A) (Adaptor protein complex AP-1 subunit mu-1) (Adaptor-related protein complex 1 subunit mu-1) (Clathrin assembly protein complex 1 mu-1 medium chain 1) (Clathrin coat assembly protein AP47) (Clathrin coat-associated protein AP47) (Golgi adaptor HA1/AP1 adaptin mu-1 subunit) (Mu-adaptin 1) (Mu1A-adaptin)
Gene: AP1M1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	32687490
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005765 - lysosomal membrane GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0016020 - membrane GO:0070062 - extracellular exosome
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 646 Hs			1 423
+	Hs
		504552 HSP7C_HUMAN (1-646): 0: 967: 100.00		AP2M1_HUMAN (3-421): 3.27e-155: 447: 38.85
+	Hs
		714045 HS71L_HUMAN (2-646): 0: 966: 82.48		AP2M1_HUMAN (3-421): 3.27e-155: 447: 38.85
+	At
		187857 HS704_ARATH (3-646): 0: 948: 76.35		AP2M_ARATH (1-421): 1.44e-160: 461: 44.04
+	At
		187756 HS701_ARATH (3-646): 0: 944: 76.35		AP2M_ARATH (1-421): 1.44e-160: 461: 44.04
+	Hs
		564149 HSP76_HUMAN (6-646): 0: 955: 77.54		AP2M1_HUMAN (3-421): 3.27e-155: 447: 38.85
+	At
		187757 HS702_ARATH (3-646): 0: 929: 75.77		AP2M_ARATH (1-421): 1.44e-160: 461: 44.04
+	Hs
		503657 HSP7C_HUMAN (1-646): 0: 967: 100.00		COPD_HUMAN (8-165): 1.23e-18: 89.7: 17.72