HitPredict

Interactor 1: HSP7C (P11142)
Heat shock cognate 71 kDa protein (EC 3.6.4.10) (Heat shock 70 kDa protein 8) (Heat shock protein family A member 8) (Lipopolysaccharide-associated protein 1) (LAP-1) (LPS-associated protein 1)
Gene: HSPA8

Interactor 2: SGT1 (Q9Y2Z0)
Protein SGT1 homolog (Protein 40-6-3) (Sgt1) (Suppressor of G2 allele of SKP1 homolog)
Gene: SUGT1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	32687490, 16501598
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0031647 - regulation of protein stability GO:0051087 - protein-folding chaperone binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 646 Hs			1 365
+	At
		1338011 HS704_ARATH (3-646): 0: 948: 76.35		SGT1B_ARATH (11-365): 2.91e-73: 233: 34.08
+	At
		612328 HS701_ARATH (3-646): 0: 944: 76.35		SGT1B_ARATH (11-365): 2.91e-73: 233: 34.08
+	At
		612327 HS701_ARATH (3-646): 0: 944: 76.35		SGT1A_ARATH (33-365): 3.96e-72: 230: 34.52
+	Mm
		926144 HSP7C_MOUSE (1-646): 0: 967: 99.85		SGTA_MOUSE (6-174): 3.04e-41: 148: 21.77
+	Mm
		926131 HSP7C_MOUSE (1-646): 0: 967: 99.85		PPP5_MOUSE (9-202): 3.13e-39: 147: 16.58
+	Hs
		213468 HSP7C_HUMAN (1-646): 0: 967: 100.00		SGTA_HUMAN (6-171): 3.42e-40: 146: 20.96
+	Hs
		503738 HSP7C_HUMAN (1-646): 0: 967: 100.00		PPP5_HUMAN (9-242): 1.39e-38: 145: 14.71
+	Hs
		564043 HSP76_HUMAN (6-646): 0: 955: 77.54		PPP5_HUMAN (9-242): 1.39e-38: 145: 14.71
+	At
		81980 HS704_ARATH (3-646): 0: 948: 76.35		OEP61_ARATH (10-361): 2.54e-39: 148: 12.53
+	At
		99225 HS701_ARATH (3-646): 0: 944: 76.35		OE64M_ARATH (7-124): 2.9e-40: 151: 22.03
+	At
		81973 HS701_ARATH (3-646): 0: 944: 76.35		OEP61_ARATH (10-361): 2.54e-39: 148: 12.53
+	At
		612321 HS701_ARATH (3-646): 0: 944: 76.35		OE64C_ARATH (4-124): 2.18e-38: 146: 21.49
+	Hs
		504014 HSP7C_HUMAN (1-646): 0: 967: 100.00		DNJC3_HUMAN (6-326): 2.67e-25: 108: 15.69
+	Hs
		713956 HS71L_HUMAN (2-646): 0: 966: 82.48		DNJC3_HUMAN (6-326): 2.67e-25: 108: 15.69
+	Hs
		564188 HSP76_HUMAN (6-646): 0: 955: 77.54		RPAP3_HUMAN (3-129): 5.92e-27: 114: 14.17
+	At
		1338008 HS704_ARATH (3-646): 0: 948: 76.35		HSOP1_ARATH (11-301): 1.95e-26: 112: 14.48
+	Hs
		174578 HSP7C_HUMAN (1-646): 0: 967: 100.00		OGT1_HUMAN (48-303): 5e-18: 87.6: 9.51
+	Hs
		871541 HSP72_HUMAN (2-646): 0: 940: 85.47		SPAG1_HUMAN (2-339): 1.63e-24: 107: 12.50
+	Hs
		297027 HSP7C_HUMAN (1-646): 0: 967: 100.00		TOM70_HUMAN (3-221): 1.5e-09: 61.4: 9.29
+	Hs
		564151 HSP76_HUMAN (6-646): 0: 955: 77.54		SGTB_HUMAN (91-296): 3.48e-10: 62.2: 12.14