HitPredict

Interactor 1: HSP7C (P11142)
Heat shock cognate 71 kDa protein (EC 3.6.4.10) (Heat shock 70 kDa protein 8) (Heat shock protein family A member 8) (Lipopolysaccharide-associated protein 1) (LAP-1) (LPS-associated protein 1)
Gene: HSPA8

Interactor 2: CD2AP (Q9Y5K6)
CD2-associated protein (Adapter protein CMS) (Cas ligand with multiple SH3 domains)
Gene: CD2AP

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	32687490
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005770 - late endosome GO:0005886 - plasma membrane GO:0045296 - cadherin binding GO:0061024 - membrane organization and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 646 Hs			1 639
+	Hs
		504539 HSP7C_HUMAN (1-646): 0: 967: 100.00		SH3K1_HUMAN (1-638): 3.71e-91: 297: 32.43
+	Hs
		503853 HSP7C_HUMAN (1-646): 0: 967: 100.00		GRB2_HUMAN (112-328): 1.9e-40: 148: 18.27
+	Hs
		713938 HS71L_HUMAN (2-646): 0: 966: 82.48		GRB2_HUMAN (112-328): 1.9e-40: 148: 18.27
+	Hs
		51051 HSP7C_HUMAN (1-646): 0: 967: 100.00		SPD2B_HUMAN (3-589): 1.72e-16: 85.7: 11.64
+	Ce
		450542 HSP1_CAEEL (1-646): 0: 937: 84.39		Q9U2T9_CAEEL (27-492): 3.56e-11: 68.5: 13.89