HitPredict

Interactor 1: HSP7C (P11142)
Heat shock cognate 71 kDa protein (EC 3.6.4.10) (Heat shock 70 kDa protein 8) (Heat shock protein family A member 8) (Lipopolysaccharide-associated protein 1) (LAP-1) (LPS-associated protein 1)
Gene: HSPA8

Interactor 2: TACC3 (Q9Y6A5)
Transforming acidic coiled-coil-containing protein 3 (ERIC-1)
Gene: TACC3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 646 Hs			1 838
+	Hs
		504067 HSP7C_HUMAN (1-646): 0: 967: 100.00		DCTN1_HUMAN (515-836): 6.94e-39: 158: 16.86
+	Hs
		504746 HSP7C_HUMAN (1-646): 0: 967: 100.00		SLK_HUMAN (364-838): 4.1e-30: 130: 13.85
+	Hs
		871777 HSP72_HUMAN (2-646): 0: 940: 85.47		SLK_HUMAN (364-838): 4.1e-30: 130: 13.85
+	Hs
		504029 HSP7C_HUMAN (1-646): 0: 967: 100.00		ROCK1_HUMAN (448-838): 4.44e-15: 81.9: 13.85
+	Hs
		254440 HSP7C_HUMAN (1-646): 0: 967: 100.00		ROCK2_HUMAN (430-838): 4.11e-12: 72.2: 11.83
+	Hs
		64578 HSP7C_HUMAN (1-646): 0: 967: 100.00		MYH7B_HUMAN (463-832): 6.29e-10: 65.3: 13.06