HitPredict

Interactor 1: HSP7C (P11142)
Heat shock cognate 71 kDa protein (EC 3.6.4.10) (Heat shock 70 kDa protein 8) (Heat shock protein family A member 8) (Lipopolysaccharide-associated protein 1) (LAP-1) (LPS-associated protein 1)
Gene: HSPA8

Interactor 2: MD1L1 (Q9Y6D9)
Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient 1-like protein 1) (MAD1-like protein 1) (Mitotic checkpoint MAD1 protein homolog) (HsMAD1) (hMAD1) (Tax-binding protein 181)
Gene: MAD1L1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 646 Hs			1 718
+	Hs
		871847 HSP72_HUMAN (2-646): 0: 940: 85.47		MD1L1_HUMAN (1-718): 9.25e-62: 221: 100.00
+	Hs
		148327 HSP7C_HUMAN (1-646): 0: 967: 100.00		CTRO_HUMAN (54-632): 5.17e-13: 75: 15.98
+	Hs
		148449 HS71L_HUMAN (2-646): 0: 966: 82.48		CTRO_HUMAN (54-632): 5.17e-13: 75: 15.98
+	Hs
		504277 HSP7C_HUMAN (1-646): 0: 967: 100.00		WDR87_HUMAN (56-522): 1.26e-12: 73.8: 19.96
+	Hs
		504448 HSP7C_HUMAN (1-646): 0: 967: 100.00		DLG5_HUMAN (125-628): 3.83e-12: 72.3: 15.98
+	Hs
		503376 HSP7C_HUMAN (1-646): 0: 967: 100.00		DESP_HUMAN (40-508): 1.22e-09: 64.2: 16.36
+	Hs
		504591 HSP7C_HUMAN (1-646): 0: 967: 100.00		CFA57_HUMAN (114-601): 1.97e-09: 63.4: 14.76
+	Hs
		148367 HSP76_HUMAN (6-646): 0: 955: 77.54		CTRO_HUMAN (54-632): 5.17e-13: 75: 15.98
+	Hs
		504493 HSP7C_HUMAN (1-646): 0: 967: 100.00		MY18A_HUMAN (44-521): 2.6e-09: 63: 15.87
+	Hs
		148576 HSP72_HUMAN (2-646): 0: 940: 85.47		CTRO_HUMAN (54-632): 5.17e-13: 75: 15.98