HitPredict

Interactor 1: A1L306 (A1L306)
TNR protein
Gene: TNR

Interactor 2: NCK2 (O43639)
Cytoplasmic protein NCK2 (Growth factor receptor-bound protein 4) (NCK adaptor protein 2) (Nck-2) (SH2/SH3 adaptor protein NCK-beta)
Gene: NCK2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.80	0.594

Property	Details
Experiments	25416956
Identification Methods	two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	SH2~fn3
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1257 Hs			1 380
+	Hs
		209134 TENR_HUMAN (1-1257): 0: 894: 100.00		NCK2_HUMAN (1-380): 6.88e-99: 300: 100.00
+	Hs
		557632 DCC_HUMAN (586-1205): 6.51e-37: 154: 10.56		NCK1_HUMAN (1-379): 7.09e-91: 279: 68.24
+	Hs
		411959 PTPRF_HUMAN (406-1176): 7.42e-90: 322: 13.85		FYN_HUMAN (7-137): 2.1e-23: 103: 20.30
+	Hs
		411565 PTPRF_HUMAN (406-1176): 7.42e-90: 322: 13.85		LCK_HUMAN (3-145): 6.3e-19: 90.2: 21.53
+	Hs
		362685 FINC_HUMAN (243-1042): 1.19e-69: 260: 22.02		FYN_HUMAN (7-137): 2.1e-23: 103: 20.30
+	Hs
		616905 PTPRB_HUMAN (234-924): 1.28e-57: 221: 17.62		CSK_HUMAN (191-378): 3.44e-32: 127: 24.87
+	Hs
		363045 FINC_HUMAN (243-1042): 1.19e-69: 260: 22.02		GRB2_HUMAN (3-61): 2.24e-18: 84.7: 28.81
+	Hs
		362705 FINC_HUMAN (243-1042): 1.19e-69: 260: 22.02		YES_HUMAN (6-120): 7.99e-16: 80.8: 23.08
+	Mm
		56907 PTPRF_MOUSE (570-1162): 2.49e-57: 220: 12.50		FYN_MOUSE (7-137): 2.1e-23: 103: 20.30
+	Hs
		412016 PTPRD_HUMAN (583-1162): 2.52e-56: 217: 11.94		FYN_HUMAN (7-137): 2.1e-23: 103: 20.30
+	Hs
		411596 PTPRB_HUMAN (234-924): 1.28e-57: 221: 17.62		LCK_HUMAN (3-145): 6.3e-19: 90.2: 21.53
+	Hs
		875821 MFAP4_HUMAN (1033-1240): 8.8e-57: 199: 46.36		GRB2_HUMAN (3-61): 2.24e-18: 84.7: 28.81