HitPredict

Interactor 1: EGR2 (P11161)
E3 SUMO-protein ligase EGR2 (EC 2.3.2.-) (AT591) (E3 SUMO-protein transferase ERG2) (Early growth response protein 2) (EGR-2) (Zinc finger protein Krox-20)
Gene: EGR2

Interactor 2: TLE5 (Q08117)
TLE family member 5 (Amino-terminal enhancer of split) (Amino enhancer of split) (Gp130-associated protein GAM) (Grg-5) (Groucho-related protein 5) (Protein ESP1) (Protein GRG) (TLE family member 5, transcriptional modulator)
Gene: TLE5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	38297188
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 476 Hs			1 197
+	Hs
		505209 EGR2_HUMAN (1-476): 0: 567: 100.00		TLE1_HUMAN (2-197): 2.47e-111: 336: 64.50
+	Hs
		505210 EGR2_HUMAN (1-476): 0: 567: 100.00		TLE3_HUMAN (2-197): 3.95e-105: 320: 61.50
+	Hs
		575391 EGR1_HUMAN (51-427): 1.31e-88: 282: 44.44		TLE4_HUMAN (2-191): 3.57e-112: 338: 68.59
+	Hs
		575390 EGR1_HUMAN (51-427): 1.31e-88: 282: 44.44		TLE3_HUMAN (2-197): 3.95e-105: 320: 61.50
+	Hs
		993497 ZNF34_HUMAN (150-395): 5.6e-74: 245: 16.60		TLE5_HUMAN (1-197): 3.1e-101: 292: 100.00
+	Hs
		993504 ZN383_HUMAN (131-310): 2.88e-54: 190: 8.00		TLE5_HUMAN (1-197): 3.1e-101: 292: 100.00